Evidence map›Paper›PMID 36292630›Full record

ArticleGenes2022

Identification of

Valeria Lucci, Elena De Marino, Daniela Tagliaferri, Stefano Amente, Alessandra Pollice, Viola Calabrò, Maria Vivo, Geppino Falco, Tiziana Angrisano

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Cripto Is Targeted by miR-1a-3p in a Mouse Model of Heart Development.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Valeria LucciDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.
Elena De MarinoDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.
Daniela TagliaferriBiogem Scarl, Istituto di Ricerche Genetiche "Gaetano Salvatore", 83031 Ariano Irpino, Italy.
Stefano AmenteDepartment of Molecular Medicine and Medical Biotechnology, University of Naples "Federico II", 80131 Naples, Italy.
Alessandra PolliceDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.ORCID 0000-0003-1619-5925
Viola CalabròDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.ORCID 0000-0002-6508-8889
Maria VivoDepartment of Chemistry and Biology, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0003-2458-4226
Geppino FalcoDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.ORCID 0000-0001-6193-7233
Tiziana AngrisanoDepartment of Biology, University of Naples "Federico II", 80147 Naples, Italy.ORCID 0000-0002-5940-5278
University of Naples Federico II · ITBiogem · ITInstitute for Experimental Endocrinology and Oncology · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Embryonic stem cells (ESCs) present a characteristic pluripotency heterogeneity correspondent to specific metastates. We recently demonstrated that retinoic acid (RA) induces an increase in a specific 2C-like metastate marked by target genes specific to the two-cell embryo stage in preimplantation. Prame (Preferentially expressed antigen in melanoma) is one of the principal actors of the pluripotency stage with a specific role in RA responsiveness. Additionally, PRAME is overexpressed in a variety of cancers, but its molecular functions are poorly understood. To further investigate Prame's downstream targets, we used a chromatin immunoprecipitation sequencing (ChIP-seq) assay in RA-enriched 2C-like metastates and identified two specific target genes,

Indexed as

Antigens, NeoplasmMelanomaCyclin-Dependent Kinase 8Cyclin-Dependent Kinase Inhibitor p19Embryonic Stem CellsHumansTretinoinAntigens, NeoplasmCDK8 protein, humanCDKN2D protein, humanCyclin-Dependent Kinase 8Cyclin-Dependent Kinase Inhibitor p19PRAME protein, humanTretinoinembryo stem cellPRAMERA-resistant

Identifiers

PMID36292630
PMCPMC9601988
OpenAlexW4297348590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.