Evidence map›Paper›PMID 36292597›Full record

ArticleGenes2022

Tierra Del Fuego: What Is Left from the Precolonial Male Lineages?

Pedro Rodrigues, Irina Florencia Velázquez, Julyana Ribeiro, Filipa Simão, António Amorim, Elizeu F Carvalho, Claudio Marcelo Bravi, Néstor Guillermo Basso, Luciano Esteban Real, Claudio Galli and 6 more

Open access · goldAbstract read
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 2 countries.

Pedro RodriguesInstituto de Investigação e Inovação em Saúde, Universidade do Porto, 4099-002 Porto, Portugal.ORCID 0000-0002-2956-1923
Irina Florencia VelázquezInstituto de Diversidad y Evolución Austral (IDEAus-CONICET), Puerto Madryn 9120, Argentina.ORCID 0000-0002-5774-9042
Julyana RibeiroDNA Diagnostic Laboratory, State University of Rio de Janeiro, Rio de Janeiro 20550-013, Brazil.
Filipa SimãoDNA Diagnostic Laboratory, State University of Rio de Janeiro, Rio de Janeiro 20550-013, Brazil.
António AmorimInstituto de Investigação e Inovação em Saúde, Universidade do Porto, 4099-002 Porto, Portugal.ORCID 0000-0002-7518-6247
Elizeu F CarvalhoDNA Diagnostic Laboratory, State University of Rio de Janeiro, Rio de Janeiro 20550-013, Brazil.
Claudio Marcelo BraviLaboratorio de Genética Molecular Poblacional, IMBICE (CCT-CONICET, CIC-PBA), Universidad Nacional de La Plata (UNLP), La Plata 1906, Argentina.ORCID 0000-0002-2499-4471
Néstor Guillermo BassoInstituto de Diversidad y Evolución Austral (IDEAus-CONICET), Puerto Madryn 9120, Argentina.
Luciano Esteban RealInstituto de Diversidad y Evolución Austral (IDEAus-CONICET), Puerto Madryn 9120, Argentina.
Claudio GalliServicio de Hemoterapia, Hospital Regional de Rio Grande, Rio Grande 9420, Argentina.
Andrea Del Carmen GonzálezServicio de Hemoterapia, CEMEP, Rio Grande 9420, Argentina.
Ariana GamulinServicio de Hemoterapia, Hospital Regional de Ushuaia, Ushuaia 9410, Argentina.
Romina SalduttiServicio de Hemoterapia, Clínica San Jorge, Ushuaia 9410, Argentina.
Maria Laura ParolinInstituto de Diversidad y Evolución Austral (IDEAus-CONICET), Puerto Madryn 9120, Argentina.ORCID 0000-0001-6726-2943
Verónica GomesInstituto de Investigação e Inovação em Saúde, Universidade do Porto, 4099-002 Porto, Portugal.ORCID 0000-0003-2815-6376
Leonor GusmãoDNA Diagnostic Laboratory, State University of Rio de Janeiro, Rio de Janeiro 20550-013, Brazil.ORCID 0000-0003-0432-6481
Consejo Nacional de Investigaciones Científicas y Técnicas · ARUniversidade do Porto · PTNational University of Tierra del Fuego · AR

Funding

Lacrimal Gland Repair Using Progenitor CellsR01EY026202 · NEI · SCRIPPS RESEARCH INSTITUTE, THE · PI MAKARENKOVA, HELEN P. · 2016 to 2025
$5.2M
6 · The paper itself

Abstract

Similar to other South American regions, Tierra del Fuego has an admixed population characterized by distinct ancestors: Native Americans who first occupied the continent, European settlers who arrived from the late 15th century onwards, and Sub-Saharan Africans who were brought to the Americas for slave labor. To disclose the paternal lineages in the current population from Tierra del Fuego, 196 unrelated males were genotyped for 23 Y-STRs and 52 Y-SNPs. Haplotype and haplogroup diversities were high, indicating the absence of strong founder or drift events. A high frequency of Eurasian haplogroups was detected (94.4%), followed by Native American (5.1%) and African (0.5%) ones. The haplogroup R was the most abundant (48.5%), with the sub-haplogroup R-S116* taking up a quarter of the total dataset. Comparative analyses with other Latin American populations showed similarities with other admixed populations from Argentina. Regarding Eurasian populations, Tierra del Fuego presented similarities with Italian and Iberian populations. In an in-depth analysis of the haplogroup R-M269 and its subtypes, Tierra del Fuego displayed a close proximity to the Iberian Peninsula. The results from this study are in line with the historical records and reflect the severe demographic change led mainly by male newcomers with paternal European origin.

Indexed as

Polymorphism, Single NucleotideRacial GroupsArgentinaHaplotypesHumansMaleadmixed populationArgentinaSouth AmericaY chromosomeY-SNPsY-STRs

Identifiers

PMID36292597
PMCPMC9601523
OpenAlexW4297237947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.