Evidence map›Paper›PMID 36292569›Full record

ArticleGenes2022

Genetic Dysruption of the Histaminergic Pathways: A Novel Deletion at the 15q21.2

Carla Lintas, Roberto Sacco, Alessia Azzarà, Ilaria Cassano, Luigi Laino, Paola Grammatico, Fiorella Gurrieri

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Etiology of Borderline Intellectual Functioning.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Carla LintasLaboratory of Medical Genetics, Medical Genetics Unit, Department of Medicine, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128 Rome, Italy.ORCID 0000-0003-1209-8554
Roberto SaccoLaboratory of Medical Genetics, Medical Genetics Unit, Department of Medicine, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128 Rome, Italy.
Alessia AzzaràLaboratory of Medical Genetics, Medical Genetics Unit, Department of Medicine, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128 Rome, Italy.ORCID 0000-0003-3639-6687
Ilaria CassanoLaboratory of Medical Genetics, Medical Genetics Unit, Department of Medicine, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128 Rome, Italy.ORCID 0000-0001-9424-4249
Luigi LainoUOC Genetica Medica, Azienda Ospedaliera S. Camillo-Forlanini, 00152 Rome, Italy.
Paola GrammaticoUOC Genetica Medica, Azienda Ospedaliera S. Camillo-Forlanini, 00152 Rome, Italy.
Fiorella GurrieriLaboratory of Medical Genetics, Medical Genetics Unit, Department of Medicine, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, 00128 Rome, Italy.
Università Campus Bio-Medico · ITAzienda Ospedaliera San Camillo-Forlanini · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The involvement of the Histaminergic System (HS) in neuropsychiatric disease is not well-documented, and few studies have described patients affected by different neuropsychiatric conditions harbouring disruptions in genes involved in the HS. In humans, histamine is synthetised from histidine by the histidine decarboxylase enzyme encoded by the

Indexed as

Histidine DecarboxylaseTourette SyndromeAdultFemaleHistamineHistidineHumansYoung AdultHistamineHistidineHistidine DecarboxylasecomorbidityHDC genehistaminergic systemneuropsychiatric disorders

Identifiers

PMID36292569
PMCPMC9602325
OpenAlexW4296745874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.