Evidence map›Paper›PMID 36292422›Full record

ArticleHealthcare (Basel, Switzerland)2022

Online Questionnaire with Fibromyalgia Patients Reveals Correlations among Type of Pain, Psychological Alterations, and Effectiveness of Non-Pharmacological Therapies.

Ilaria Demori, Elena Molinari, Fabio Rapallo, Viviana Mucci, Lucio Marinelli, Serena Losacco, Bruno Burlando

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. The complexity of pain in osteoarthritis.Nature reviews. Rheumatology · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. What Do We Know about Nociplastic Pain?Healthcare (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ilaria DemoriDepartment of Earth, Environmental and Life Sciences (DISTAV), University of Genova, Corso Europa, 26, 16132 Genova, Italy.ORCID 0000-0002-6894-8223
Elena MolinariClinical Psychology Unit, E.O. Ospedali Galliera, Via Mura delle Cappuccine 14, 16128 Genova, Italy.
Fabio RapalloDepartment of Economics (DIEC), University of Genova, Via Vivaldi, 5, 16126 Genova, Italy.ORCID 0000-0001-6451-5140
Viviana MucciSchool of Science, Western Sydney University, Penrith, NSW 2150, Australia.
Lucio MarinelliDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, DINOGMI, University of Genova, Largo P. Daneo 3, 16132 Genova, Italy.ORCID 0000-0003-0620-7654
Serena LosaccoDepartment of Pharmacy, DIFAR, University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.
Bruno BurlandoDepartment of Pharmacy, DIFAR, University of Genova, Viale Benedetto XV 3, 16132 Genova, Italy.

Funding

University of Genoa 100006-2020-SA-FRA_001University of Genoa 100022-2012-DIP_01
6 · The paper itself

Abstract

Fibromyalgia (FM) is a chronic pain syndrome with an unclear etiology. In addition to pain, FM patients suffer from a diverse array of symptoms and comorbidities, encompassing fatigue, cognitive dysfunction, mood disorders, sleep deprivation, and dizziness. Due to the complexity of FM, the diagnosis and treatment of it are highly challenging. The aim of the present work was to investigate some clinical and psychological characteristics of FM patients, and to uncover possible correlations with pharmacological and non-pharmacological therapies. We conducted a cross-sectional, questionnaire-based study aimed at evaluating pain, psychological traits, and the self-perceived effectiveness of pharmacological and non-pharmacological treatments in an Italian population of FM patients. Descriptive statistics, correlation, and inference analyses were performed. We found a prevalence of a neuropathic/nociplastic type of pain, which correlated with psychological traits such as anxiety, low mood, psychophysical discomfort, and the inability to relax. The pain type and psychological traits proved to play a role in determining the self-perceived effectiveness of therapeutic interventions. Patients revealed a better response to non-pharmacological therapies, particularly dietary interventions, relaxation techniques, and psychotherapy rather than pharmacological interventions. The sum of our data indicates that for better outcomes, the type of pain and psychological traits should be considered for tailor-made treatments considering non-pharmacological protocols as a complement to the use of drugs.

Indexed as

neuropathic painnociplastic painnon-pharmacological therapiesonline surveypatient managementpsycho-neuro-endocrine-immunology

Identifiers

PMID36292422
PMCPMC9602604

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.