Evidence map›Paper›PMID 36292245›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Platelet-to-White Blood Cell Ratio: A Feasible Biomarker for Pyogenic Liver Abscess.

Dong-Gyun Ko, Ji-Won Park, Jung-Hee Kim, Jang-Han Jung, Hyoung-Su Kim, Ki-Tae Suk, Myoung-Kuk Jang, Sang-Hoon Park, Myung-Seok Lee, Dong-Joon Kim and 1 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dong-Gyun KoDepartment of Physiology, College of Medicine, Hallym University, Chuncheon 24252, Korea.ORCID 0000-0002-9597-8436
Ji-Won ParkDepartment of Internal Medicine, Hallym University Sacred Heart Hospital, Medical Center, 22, Gwanpyeong-ro 170 Beon-gil, Anyang-si 14068, Korea.ORCID 0000-0002-5884-9993
Jung-Hee KimDepartment of Internal Medicine, Dongtan Sacred Heart Hospital of Hallym University Medical Center, Hwaseong-si 18450, Korea.ORCID 0000-0001-5435-6166
Jang-Han JungDepartment of Internal Medicine, Dongtan Sacred Heart Hospital of Hallym University Medical Center, Hwaseong-si 18450, Korea.ORCID 0000-0001-7875-2868
Hyoung-Su KimInstitute for Liver and Digestive Diseases, Hallym University, Chuncheon 24252, Korea.ORCID 0000-0002-2394-1095
Ki-Tae SukInstitute for Liver and Digestive Diseases, Hallym University, Chuncheon 24252, Korea.ORCID 0000-0002-9206-9245
Myoung-Kuk JangInstitute for Liver and Digestive Diseases, Hallym University, Chuncheon 24252, Korea.
Sang-Hoon ParkDepartment of Internal Medicine, Kangnam Sacred Heart Hospital of Hallym University Medical Center, 1, Singil-ro, Seoul 07441, Korea.
Myung-Seok LeeDepartment of Internal Medicine, Kangnam Sacred Heart Hospital of Hallym University Medical Center, 1, Singil-ro, Seoul 07441, Korea.
Dong-Joon KimInstitute for Liver and Digestive Diseases, Hallym University, Chuncheon 24252, Korea.ORCID 0000-0002-5792-1500
Sung-Eun KimDepartment of Internal Medicine, Hallym University Sacred Heart Hospital, Medical Center, 22, Gwanpyeong-ro 170 Beon-gil, Anyang-si 14068, Korea.ORCID 0000-0001-6236-780X

Funding

National Research Foundation of Korea 2020R1A6A103043026
6 · The paper itself

Abstract

The platelet-to-white blood cell ratio (PWR) has been reported to predict the severity of patients with various diseases. However, no previous studies have assessed the use of the PWR as a prognostic marker for pyogenic liver abscesses (PLA). This observational retrospective study was performed between January 2008 and December 2017, including 833 patients with PLA from multiple centers. The enrolled patients, on average, had a PWR of 17.05, and 416 patients had a PWR lower than 17.05. A total of 260 patients (31.2%) with PLA showed complications of metastatic infection, pleural effusion and abscess rupture. A low PWR level was identified as a strong risk factor for metastatic infection and pleural effusion. The low PWR group also had a longer hospital stay. In the multivariate analysis, old age, anemia, albumin and CRP levels and unidentified pathogens were significant factors for low PWR levels. A low PWR, old age, male sex, abscess size, albumin, ALP and unidentified causative pathogens showed significant associations with a hospital stay longer than 28 days. As a result, PLA patients presenting with a low PWR were shown to have more complications and a poor prognosis. Considering its cost-effectiveness, PWR could be a novel biomarker used to predict a prognosis of PLA.

Indexed as

platelet-to-white blood cell ratiopleural effusionpyogenic liver abscess

Identifiers

PMID36292245
PMCPMC9600737

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.