Evidence map›Paper›PMID 36292229›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Factors Influencing the Prognosis of Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Alaa Ghali, Carole Lacout, Jacques-Olivier Fortrat, Karine Depres, Maria Ghali, Christian Lavigne

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Intersectionality and Long Covid: Understanding the Lived Experiences of Ethnic Minority Groups in the United Kingdom.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  9. Neuroimmune pathophysiology of long COVID.Psychiatry and clinical neurosciences · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alaa GhaliDepartment of Internal Medicine and Clinical Immunology, Angers University Hospital, F-49000 Angers, France.ORCID 0000-0003-2040-3387
Carole LacoutDepartment of Internal Medicine and Clinical Immunology, Angers University Hospital, F-49000 Angers, France.ORCID 0000-0003-2875-6048
Jacques-Olivier FortratDepartment of Vascular Medicine, Angers University Hospital, F-49000 Angers, France.ORCID 0000-0002-9272-0157
Karine DepresDepartment of Internal Medicine and Clinical Immunology, Angers University Hospital, F-49000 Angers, France.
Maria GhaliDepartment of General Medicine, Faculty of Medicine of Angers, University of Angers, F-49000 Angers, France.
Christian LavigneDepartment of Internal Medicine and Clinical Immunology, Angers University Hospital, F-49000 Angers, France.ORCID 0000-0002-2538-0076

Funding

Association Française de Syndrome de Fatigue Chronique Article processing charges
6 · The paper itself

Abstract

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a long-term debilitating multisystem condition with poor prognosis. Studies that examined predictors of ME/CFS outcomes yielded contradictory results. We aimed to explore epidemiological and clinical prognostic factors of ME/CFS using operationalized criteria for recovery/improvement. Adult ME/CFS patients who attended the Internal Medicine Department of Angers University Hospital, Angers, France between October 2011 and December 2019, and were followed up until December 2020, were included retrospectively. Their medical records were reviewed for data collection. Patients were classified into two groups according to the presence or absence of recovery/improvement (R/I) and compared for epidemiological characteristics, fatigue features, post-exertional malaise severity, clinical manifestations, and comorbidities. The subgroups of recovered and significantly improved patients were then compared. 168 patients were included. Recovery and improvement rates were 8.3% and 4.8%, respectively. Older age at disease onset was associated with R/I (OR 1.06 [95% CI 1.007-1.110] (

Indexed as

age at disease onsetdiagnostic delaymyalgic encephalomyelitis/chronic fatigue syndromeprognosis

Identifiers

PMID36292229
PMCPMC9600584

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.