Evidence map›Paper›PMID 36292204›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Comparison of Spectral-Domain OCT versus Swept-Source OCT for the Detection of Deep Optic Disc Drusen.

Simon P Rothenbuehler, Lasse Malmqvist, Mohamed Belmouhand, Jakob Bjerager, Peter M Maloca, Michael Larsen, Steffen Hamann

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Low-Cost and Fast Epiretinal Membrane Detection and Quantification Based on SD-OCT.IEEE access : practical innovations, open solutions · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Simon P RothenbuehlerDepartment of Ophthalmology, Rigshospitalet, University of Copenhagen, 2600 Glostrup, Denmark.ORCID 0000-0002-5223-6483
Lasse MalmqvistDepartment of Ophthalmology, Rigshospitalet, University of Copenhagen, 2600 Glostrup, Denmark.
Mohamed BelmouhandDepartment of Ophthalmology, Rigshospitalet, University of Copenhagen, 2600 Glostrup, Denmark.ORCID 0000-0001-5855-4733
Jakob BjeragerDepartment of Ophthalmology, Rigshospitalet, University of Copenhagen, 2600 Glostrup, Denmark.ORCID 0000-0002-6620-6242
Peter M MalocaDepartment of Ophthalmology, OCTlab, University Hospital Basel, 4031 Basel, Switzerland.
Michael LarsenDepartment of Ophthalmology, Rigshospitalet, University of Copenhagen, 2600 Glostrup, Denmark.ORCID 0000-0002-5172-5891
Steffen HamannDepartment of Ophthalmology, Rigshospitalet, University of Copenhagen, 2600 Glostrup, Denmark.
University of Copenhagen · DKMoorfields Eye Hospital NHS Foundation Trust · GB

Funding

Alfred-Vogt-Foundation, OPOS Foundation, Nachwuchsfoerderung Universität Basel 000
6 · The paper itself

Abstract

Deep optic disc drusen (ODD) are located below Bruch's membrane opening (BMO) and may go undetected due to the challenges in imaging them. The purpose of this study is a head-to-head comparison of currently widely used imaging technologies: swept-source optical coherence tomography (SS-OCT; DRI OCT-1 Triton, Topcon) and enhanced depth imaging spectral-domain optical coherence tomography (EDI SD-OCT; Spectralis OCT, Heidelberg Engineering) for the detection of deep ODD and associated imaging features. The eyes included in this study had undergone high-resolution imaging via both EDI SD-OCT and SS-OCT volume scans, which showed at least one deep ODD or a hyperreflective line (HL). Grading was performed by three graders in a masked fashion. The study findings are based on 46 B-scan stacks of 23 eyes including a total of 7981 scans. For scan images with ODD located above or below the level of BMO, no significant difference was found between the two modalities compared in this study. However, for HLs and other features, EDI SD-OCT scan images had better visualization and less artifacts. Although SS-OCT offers deep tissue visualization, it did not appear to offer any advantage in ODD detection over a dense volume scan via EDI SD-OCT with B-scan averaging.

Indexed as

comparisonenhanced depth imagingoptical coherence tomographyoptic disc drusenoptic nerve head drusenspectral-domainswept-source

Identifiers

PMID36292204
PMCPMC9600200
OpenAlexW4306403424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.