Evidence map›Paper›PMID 36292145›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Application of CRISPR/Cas Systems in the Nucleic Acid Detection of Infectious Diseases.

Junwei Li, Yuexia Wang, Bin Wang, Juan Lou, Peng Ni, Yuefei Jin, Shuaiyin Chen, Guangcai Duan, Rongguang Zhang

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Junwei LiInternational School of Public Health and One Health, First Affiliated Hospital of Hainan Medical University, Haikou 570102, China.
Yuexia WangDepartment of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Bin WangDepartment of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Juan LouDepartment of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Peng NiDepartment of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Yuefei JinDepartment of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0002-1523-0808
Shuaiyin ChenDepartment of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0001-6129-0310
Guangcai DuanDepartment of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou 450001, China.
Rongguang ZhangInternational School of Public Health and One Health, First Affiliated Hospital of Hainan Medical University, Haikou 570102, China.ORCID 0000-0001-9961-2434

Funding

Hainan Medical University Talent Project XRC202031Hainan Natural Science Foundation 820CXTD438National Natural Science Foundation of China 82160634
6 · The paper itself

Abstract

The CRISPR/Cas system is a protective adaptive immune system against attacks from foreign mobile genetic elements. Since the discovery of the excellent target-specific sequence recognition ability of the CRISPR/Cas system, the CRISPR/Cas system has shown excellent performance in the development of pathogen nucleic-acid-detection technology. In combination with various biosensing technologies, researchers have made many rapid, convenient, and feasible innovations in pathogen nucleic-acid-detection technology. With an in-depth understanding and development of the CRISPR/Cas system, it is no longer limited to CRISPR/Cas9, CRISPR/Cas12, and other systems that had been widely used in the past; other CRISPR/Cas families are designed for nucleic acid detection. We summarized the application of CRISPR/Cas-related technology in infectious-disease detection and its development in SARS-CoV-2 detection.

Indexed as

biosensing technologiesCRISPR/Cas systemdiagnosespathogen nucleic acidsSARS-CoV-2

Identifiers

PMID36292145
PMCPMC9600689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.