Evidence map›Paper›PMID 36292090›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Nuclear Expression of β-Catenin Is Associated with Improved Outcomes in Endometrial Cancer.

Valeria Masciullo, Tommaso Susini, Giacomo Corrado, Marina Stepanova, Alessandro Baroni, Irene Renda, Francesca Castiglione, Corrado Minimo, Alfonso Bellacosa, Benito Chiofalo and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Valeria MasciulloDivision of Gynecologic Surgery, Department of Woman, Child and Public Health, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Catholic University of Sacred Heart, 00168 Rome, Italy.
Tommaso SusiniDepartment of Obstetrics and Gynecology, University of Florence, 50121 Florence, Italy.
Giacomo CorradoDivision of Gynecologic Oncology, Department of Woman, Child and Public Health, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Catholic University of Sacred Heart, 00168 Rome, Italy.ORCID 0000-0002-8319-6146
Marina StepanovaCancer Signaling and Epigenetics Program and Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Alessandro BaroniDivision of Gynecologic Surgery, Department of Woman, Child and Public Health, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Catholic University of Sacred Heart, 00168 Rome, Italy.
Irene RendaDepartment of Pathology, University of Florence, 50121 Florence, Italy.
Francesca CastiglioneDepartment of Pathology, University of Florence, 50121 Florence, Italy.
Corrado MinimoDepartment of Pathology and Laboratory Medicine, Albert Einstein Medical Center, Philadelphia, PA 19111, USA.
Alfonso BellacosaCancer Signaling and Epigenetics Program and Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.
Benito ChiofaloGynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, 00128 Rome, Italy.ORCID 0000-0003-2801-2962
Enrico VizzaGynecologic Oncology Unit, Department of Experimental Clinical Oncology, IRCCS Regina Elena National Cancer Institute, 00128 Rome, Italy.
Giovanni ScambiaDivision of Gynecologic Oncology, Department of Woman, Child and Public Health, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Catholic University of Sacred Heart, 00168 Rome, Italy.
University of Florence · ITAgostino Gemelli University Polyclinic · ITFox Chase Cancer Center · USIstituti di Ricovero e Cura a Carattere Scientifico · ITEinstein Medical Center Philadelphia · US

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Dietmar J Kappes · 1985 to 2026
$138.8M
NCI NIH HHS P30 CA006927
6 · The paper itself

Abstract

Beta-catenin is involved in intercellular adhesion and participates in the Wnt signaling pathway. This study evaluated the expression pattern and prognostic value of β-catenin in a series of endometrial carcinoma patients. Immunohistochemical analyses were used to assess the expression and subcellular localization of β-catenin from tissue sections of 74 patients with endometrial carcinoma. No correlation was found between beta-catenin expression and clinicopathological parameters. Patients expressing nuclear β-catenin (

Indexed as

endometrial cancerprognosisβ-catenin

Identifiers

PMID36292090
PMCPMC9600744
OpenAlexW4303628083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.