Evidence map›Paper›PMID 36292071›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Frequency of Missed Findings on Chest Radiographs (CXRs) in an International, Multicenter Study: Application of AI to Reduce Missed Findings.

Parisa Kaviani, Mannudeep K Kalra, Subba R Digumarthy, Reya V Gupta, Giridhar Dasegowda, Ammar Jagirdar, Salil Gupta, Preetham Putha, Vidur Mahajan, Bhargava Reddy and 4 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Patient-centered AI.Frontiers in digital health · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Parisa KavianiDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0003-0911-7507
Mannudeep K KalraDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Subba R DigumarthyDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Reya V GuptaDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Giridhar DasegowdaDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.ORCID 0000-0001-9246-8265
Ammar JagirdarQure.ai, Mumbai 400063, India.
Salil GuptaCARPL, New Delhi 110016, India.
Preetham PuthaQure.ai, Mumbai 400063, India.
Vidur MahajanCARPL, New Delhi 110016, India.
Bhargava ReddyQure.ai, Mumbai 400063, India.ORCID 0000-0001-7643-7346
Vasanth K VenugopalCARPL, New Delhi 110016, India.ORCID 0000-0003-1357-6941
Manoj TadepalliQure.ai, Mumbai 400063, India.
Bernardo C BizzoDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.
Keith J DreyerDepartment of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMissed findings in chest X-ray interpretation are common and can have serious consequences.

methodsOur study included 2407 chest radiographs (CXRs) acquired at three Indian and five US sites. To identify CXRs reported as normal, we used a proprietary radiology report search engine based on natural language processing (mPower, Nuance). Two thoracic radiologists reviewed all CXRs and recorded the presence and clinical significance of abnormal findings on a 5-point scale (1-not important; 5-critical importance). All CXRs were processed with the AI model (Qure.ai) and outputs were recorded for the presence of findings. Data were analyzed to obtain area under the ROC curve (AUC).

resultsOf 410 CXRs (410/2407, 18.9%) with unreported/missed findings, 312 (312/410, 76.1%) findings were clinically important: pulmonary nodules (

conclusionA substantial number of important CXR findings are missed; the AI model can help to identify and reduce the frequency of important missed findings in a generalizable manner.

Indexed as

chest X-raychest X-ray interpretationmissed findingradiology

Identifiers

PMID36292071
PMCPMC9600490

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.