Evidence map›Paper›PMID 36292041›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Significance of Indoleamine 2,3-Dioxygenase Expression in the Immunological Response of Kidney Graft Recipients.

Krzysztof Wiśnicki, Piotr Donizy, Agata Remiorz, Dariusz Janczak, Magdalena Krajewska, Mirosław Banasik

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Krzysztof WiśnickiDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-1073-5759
Piotr DonizyDepartment of Clinical and Experimental Pathology, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0002-8729-6216
Agata RemiorzDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0001-8217-9750
Dariusz JanczakDepartment of Vascular, General and Transplantation Surgery, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0003-4671-9128
Magdalena KrajewskaDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0002-2632-2409
Mirosław BanasikDepartment of Nephrology and Transplantation Medicine, Wroclaw Medical University, 50-556 Wroclaw, Poland.ORCID 0000-0002-0588-1551
Wroclaw Medical University · PL

Funding

Wrocław Medical University C160.22.080
6 · The paper itself

Abstract

Kidney transplantation is unquestionably the most advantageous and preferred treatment when patients with end-stage renal disease are considered. It does have a substantially positive influence on both the quality and expectancy of their lives. Thus, it is quintessential to extend the survival rate of kidney grafts. On account of T-cell-focused treatment, this is being exponentially achieved. The kynurenine pathway, as an immunosuppressive apparatus, and indoleamine 2,3-dioxygenase (IDO1), as its main regulator, are yet to be exhaustively explored. This review presents the recognised role of IDO1 and its influence on the kynurenine pathway, with emphasis on immunosuppression in kidney transplant protection.

Indexed as

antibodygraftimmune responseimmune toleranceimmunosuppressionindoleamine 2,3-dioxygenase (IDO1)kidney transplantkynurenine pathwayrejection

Identifiers

PMID36292041
PMCPMC9600090
OpenAlexW4297464172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.