Evidence map›Paper›PMID 36292021›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Deep Learning Assessment for Mining Important Medical Image Features of Various Modalities.

Ioannis D Apostolopoulos, Nikolaos D Papathanasiou, Nikolaos I Papandrianos, Elpiniki I Papageorgiou, George S Panayiotakis

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ioannis D ApostolopoulosDepartment of Medical Physics, School of Medicine, University of Patras, 26504 Rio, Greece.ORCID 0000-0001-6439-9282
Nikolaos D PapathanasiouLaboratory of Nuclear Medicine, University Hospital of Patras, 26504 Rio, Greece.
Nikolaos I PapandrianosDepartment of Energy Systems, Gaiopolis Campus, University of Thessaly, 41500 Larisa, Greece.ORCID 0000-0001-5416-1991
Elpiniki I PapageorgiouDepartment of Energy Systems, Gaiopolis Campus, University of Thessaly, 41500 Larisa, Greece.ORCID 0000-0003-2498-9661
George S PanayiotakisDepartment of Medical Physics, School of Medicine, University of Patras, 26504 Rio, Greece.

Funding

Hellenic Foundation for Research and Innovation (H.F.R.I.) 3656
6 · The paper itself

Abstract

Deep learning (DL) is a well-established pipeline for feature extraction in medical and nonmedical imaging tasks, such as object detection, segmentation, and classification. However, DL faces the issue of explainability, which prohibits reliable utilisation in everyday clinical practice. This study evaluates DL methods for their efficiency in revealing and suggesting potential image biomarkers. Eleven biomedical image datasets of various modalities are utilised, including SPECT, CT, photographs, microscopy, and X-ray. Seven state-of-the-art CNNs are employed and tuned to perform image classification in tasks. The main conclusion of the research is that DL reveals potential biomarkers in several cases, especially when the models are trained from scratch in domains where low-level features such as shapes and edges are not enough to make decisions. Furthermore, in some cases, device acquisition variations slightly affect the performance of DL models.

Indexed as

biomarkersdeep learningfeature extractionmedical imaging

Identifiers

PMID36292021
PMCPMC9600450

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.