Evidence map›Paper›PMID 36291984›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Residual Tumor Patterns of Breast Cancer on MRI after Neo-Adjuvant Chemotherapy: Impact on Clinicopathologic Factors and Prognosis.

Yoon Jin Cha, Na Lae Eun, Dooreh Kim, Soong June Bae, Sung Gwe Ahn, Joon Jeong, Woo-Chan Park, Yangkyu Lee, Chang Ik Yoon

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yoon Jin ChaDepartment of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea.ORCID 0000-0002-5967-4064
Na Lae EunDepartment of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea.ORCID 0000-0002-7299-3051
Dooreh KimDivision of Breast Surgery, Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Seoul, Seoul 06591, Korea.
Soong June BaeInstitute of Breast Cancer Precision Medicine, Yonsei University College of Medicine, Seoul 06273, Korea.ORCID 0000-0002-0012-9694
Sung Gwe AhnInstitute of Breast Cancer Precision Medicine, Yonsei University College of Medicine, Seoul 06273, Korea.ORCID 0000-0002-8778-9686
Joon JeongInstitute of Breast Cancer Precision Medicine, Yonsei University College of Medicine, Seoul 06273, Korea.ORCID 0000-0003-0397-0005
Woo-Chan ParkDivision of Breast Surgery, Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Seoul, Seoul 06591, Korea.
Yangkyu LeeDepartment of Pathology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea.
Chang Ik YoonDivision of Breast Surgery, Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Seoul, Seoul 06591, Korea.ORCID 0000-0002-7273-8886
Yonsei University · KRUniversity of Seoul · KR

Funding

National Research Foundation of Korea NRF-2021R1G1A109359612Yonsei University College of Medicine 6-2021-0159, 6-2022-0123
6 · The paper itself

Abstract

(1) Background: Residual breast cancer after neoadjuvant chemotherapy (NAC) could have a variable image pattern on a follow-up breast magnetic resonance image (MRI). In this study, we compared the clinical outcome of breast cancer patients with different residual tumor patterns (RTP) on a breast MRI after NAC. (2) Methods: A total of 91 patients with breast cancer who received NAC and subsequent curative surgery were selected. All included patient had residual breast cancer after NAC and showed a partial response on a breast MRI. Pre- and post-treatment were reviewed by an experienced radiologist to evaluate different RTP, and classified into two groups: concentric and scattered patterns. The clinicopathologic parameters and survival outcomes [recurrence-free survival (RFS) and distant metastasis-free survival (DMFS)] were analyzed according to different RTP. (3) Results: Patients with a scattered pattern had a larger extent of pre-treated non-mass enhancement and more frequently received total mastectomy. With a median follow-up period of 37 months, RTP were not significantly associated with RFS or DMFS. (4) Conclusions: In the patients with residual breast cancer after NAC, RTP on an MRI had no effect on the patients' clinical outcome. The curative resection of the tumor bed and securing the negative resection margins appear to be important in the treatment of patients with residual breast cancer after NAC.

Indexed as

breast neoplasmsmagnetic resonance imagingneoadjuvant therapyprognosis

Identifiers

PMID36291984
PMCPMC9600236
OpenAlexW4297151554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.