Evidence map›Paper›PMID 36291968›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Performance Analysis of Self-Collected Nasal and Oral Swabs for Detection of SARS-CoV-2.

Ho-Jae Lim, Young-Hyun Baek, Min-Young Park, Jae-Hyun Yang, Min-Jin Kim, Nackmoon Sung, Yong-Hak Sohn, Sun-Hwa Lee, Jung-Eun Park, Yong-Jin Yang

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ho-Jae LimDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Korea.ORCID 0000-0003-0115-5170
Young-Hyun BaekDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Korea.ORCID 0000-0002-6894-9293
Min-Young ParkDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Korea.
Jae-Hyun YangPaul F. Glenn Center for Biology of Aging Research, Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.
Min-Jin KimDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Korea.ORCID 0000-0003-1645-6101
Nackmoon SungClinical Research Institute, Seegene Medical Foundation, Seoul 04805, Korea.ORCID 0000-0001-8951-163X
Yong-Hak SohnDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Korea.
Sun-Hwa LeeDepartment of Laboratory Medicine, Seegene Medical Foundation, Seoul 04805, Korea.
Jung-Eun ParkDepartment of Integrative Biological Sciences & BK21 FOUR Educational Research Group for Age-Associated Disorder Control Technology, Chosun University, Gwangju 61452, Korea.ORCID 0000-0001-8789-9829
Yong-Jin YangDepartment of Molecular Diagnostics, Seegene Medical Foundation, Seoul 04805, Korea.ORCID 0000-0002-6153-9646
Chosun University · KRHarvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the third highly pathogenic human coronavirus and is rapidly transmitted by infected individuals regardless of their symptoms. During the COVID-19 pandemic, owing to the dearth of skilled healthcare workers (HCWs) to collect samples for early diagnosis, self-collection emerged as a viable alternative. To evaluate the reliability of self-collection, we compared the virus detection rate using 3990 self-collected swabs and HCW-collected swabs, procured from the same individuals and collected immediately after the self-collection. The results of multiplex reverse-transcription quantitative polymerase chain reaction revealed that the viral load in the HCW-collected swabs was marginally (18.4-28.8 times) higher than that in self-collected swabs. Self-collection showed no significant difference in sensitivity and specificity from HCW-collection (κ = 0.87, McNemar's test;

Indexed as

HCW-collectionlarge-scale samplingmRT-qPCRSARS-CoV-2self-collectionviral load

Identifiers

PMID36291968
PMCPMC9600397
OpenAlexW4296991880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.