Evidence map›Paper›PMID 36291868›Full record

ReviewCancers2022

Is Fasting Good When One Is at Risk of Liver Cancer?

Iulia Minciuna, Laurens A van Kleef, Horia Stefanescu, Bogdan Procopet

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Intermittent fasting and liver disease: Insights from the Ramadan model.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026
    Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Iulia MinciunaRegional Institute of Gastroenterology and Hepatology Octavian Fodor, 400394 Cluj-Napoca, Romania.
Laurens A van KleefDepartment of Gastroenterology and Hepatology, Erasmus MC University Medical Centre, 3015 GD Rotterdam, The Netherlands.
Horia StefanescuRegional Institute of Gastroenterology and Hepatology Octavian Fodor, 400394 Cluj-Napoca, Romania.ORCID 0000-0002-4034-5471
Bogdan ProcopetRegional Institute of Gastroenterology and Hepatology Octavian Fodor, 400394 Cluj-Napoca, Romania.
Iuliu Hațieganu University of Medicine and Pharmacy · ROErasmus MC · NLInstitutul Regional de Gastroenterologie Prof. Dr. Octavian Fodor · RO

Funding

Romanian National Council for Scientific Research PN-III-P4-ID-PCE2020-1091
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC), one of the leading causes of cancer-related deaths worldwide, is a multistep process that usually develops in the background of cirrhosis, but also in a non-cirrhotic state in patients with non-alcoholic fatty liver disease (NAFLD) or viral hepatis. Emerging evidence suggests that intermittent fasting can reduce the risk of cancer development and could improve response and tolerance to treatment through the metabolic and hormonal adaptations induced by the low energy availability that finally impairs cancer cells' adaptability, survival and growth. The current review will outline the beneficial effects of fasting in NAFLD/NASH patients and the possible mechanisms that can prevent HCC development, including circadian clock re-synchronization, with a special focus on the possibility of applying this dietary intervention to cirrhotic patients.

Indexed as

cirrhosishepatocellular carcinomaintermittent fastingnon-alcoholic fatty liver diseasetime-restricted feeding

Identifiers

PMID36291868
PMCPMC9600146
OpenAlexW4306653038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.