Evidence map›Paper›PMID 36291864›Full record

ArticleCancers2022

Efficient Synthesis with Green Chemistry Approach of Novel Pharmacophores of Imidazole-Based Hybrids for Tumor Treatment: Mechanistic Insights from In Situ to In Silico.

Majid Khan, Syed Raza Shah, Faizullah Khan, Sobia Ahsan Halim, Shaikh Mizanoor Rahman, Mohammad Khalid, Ajmal Khan, Ahmed Al-Harrasi

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Drug Design of Carbonic Anhydrase Inhibitors.Sub-cellular biochemistry · 2026
    Review
  2. Biochemical andFrontiers in chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Majid KhanNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, Nizwa P.O. Box 33, Oman.ORCID 0000-0002-9287-2046
Syed Raza ShahNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, Nizwa P.O. Box 33, Oman.
Faizullah KhanNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, Nizwa P.O. Box 33, Oman.
Sobia Ahsan HalimNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, Nizwa P.O. Box 33, Oman.
Shaikh Mizanoor RahmanNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, Nizwa P.O. Box 33, Oman.ORCID 0000-0002-4879-2663
Mohammad KhalidDepartment of Pharmaceutics, College of Pharmacy, King Khalid University, Abha 62529, Saudi Arabia.ORCID 0000-0003-1479-6487
Ajmal KhanNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, Nizwa P.O. Box 33, Oman.
Ahmed Al-HarrasiNatural and Medical Sciences Research Center, University of Nizwa, 616 Birkat Al Mauz, Nizwa P.O. Box 33, Oman.ORCID 0000-0002-0815-5942
University of Nizwa · OMAbdul Wali Khan University Mardan · PKKing Khalid University · SAUniversity of Karachi · PK

Funding

King Khalid University RGP.2/64/43The Research Council BFP/RGP/HSS/19/198
6 · The paper itself

Abstract

Imidazole-based pyrimidine hybrids are considered a remarkable class of compounds in pharmaceutical chemistry. Here, we report the anticancer bioactivities of eleven imidazole-based pyrimidine hybrids (

Indexed as

anticancercytotoxicityimidazole-based hybrids with hydroxyethyl and pyrimidinein silico molecular dockingmechanistic studies

Identifiers

PMID36291864
PMCPMC9600394
OpenAlexW4306652922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.