Evidence map›Paper›PMID 36291825›Full record

ArticleCancers2022

Identification of Disparities in Personalized Cancer Care-A Joint Approach of the German WERA Consortium.

Florian Lüke, Florian Haller, Kirsten Utpatel, Markus Krebs, Norbert Meidenbauer, Alexander Scheiter, Silvia Spoerl, Daniel Heudobler, Daniela Sparrer, Ulrich Kaiser and 30 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors at 8 institutions in 1 country.

Florian LükeDepartment of Internal Medicine III, Hematology and Oncology, University Hospital Regensburg, 93053 Regensburg, Germany.ORCID 0000-0001-5252-287X
Florian HallerInstitute of Pathology, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, 91054 Erlangen, Germany.
Kirsten UtpatelComprehensive Cancer Center Ostbayern, 93053 Regensburg, Germany.
Markus KrebsComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.
Norbert MeidenbauerComprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany.
Alexander ScheiterComprehensive Cancer Center Ostbayern, 93053 Regensburg, Germany.ORCID 0000-0001-6734-261X
Silvia SpoerlComprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany.
Daniel HeudoblerDepartment of Internal Medicine III, Hematology and Oncology, University Hospital Regensburg, 93053 Regensburg, Germany.ORCID 0000-0002-8790-4584
Daniela SparrerDepartment of Internal Medicine III, Hematology and Oncology, University Hospital Regensburg, 93053 Regensburg, Germany.
Ulrich KaiserDepartment of Internal Medicine III, Hematology and Oncology, University Hospital Regensburg, 93053 Regensburg, Germany.ORCID 0000-0003-0321-5245
Felix KeilComprehensive Cancer Center Ostbayern, 93053 Regensburg, Germany.ORCID 0000-0002-0651-5916
Christoph SchubartInstitute of Pathology, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, 91054 Erlangen, Germany.ORCID 0000-0003-0084-9330
Lars TögelInstitute of Pathology, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, 91054 Erlangen, Germany.
Sabine EinhellDepartment of Internal Medicine III, Hematology and Oncology, University Hospital Regensburg, 93053 Regensburg, Germany.
Wolfgang DietmaierComprehensive Cancer Center Ostbayern, 93053 Regensburg, Germany.
Ralf HussMedical Faculty, Institute of Pathology and Molecular Diagnostics, University of Augsburg, 86156 Augsburg, Germany.
Sebastian DintnerMedical Faculty, Institute of Pathology and Molecular Diagnostics, University of Augsburg, 86156 Augsburg, Germany.
Sebastian SommerComprehensive Cancer Center Augsburg, 86156 Augsburg, Germany.
Frank JordanComprehensive Cancer Center Augsburg, 86156 Augsburg, Germany.
Maria-Elisabeth GoebelerComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.
Michaela MetzComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.
Diana HaakeComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.
Mithun ScheyttComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.
Elena Gerhard-HartmannComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.
Katja MaurusComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.
Stephanie BrändleinComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.
Andreas RosenwaldComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.
Arndt HartmannInstitute of Pathology, Friedrich-Alexander University Erlangen-Nuremberg, University Hospital Erlangen, 91054 Erlangen, Germany.
Bruno MärklMedical Faculty, Institute of Pathology and Molecular Diagnostics, University of Augsburg, 86156 Augsburg, Germany.ORCID 0000-0002-7704-850X
Hermann EinseleBavarian Center for Cancer Research (BZKF), 91054 Erlangen, Germany.ORCID 0000-0002-7680-0819
Andreas MackensenComprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany.
Wolfgang HerrDepartment of Internal Medicine III, Hematology and Oncology, University Hospital Regensburg, 93053 Regensburg, Germany.
Volker KunzmannComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.
Ralf BargouComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.
Matthias W BeckmannComprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany.
Tobias PukropDepartment of Internal Medicine III, Hematology and Oncology, University Hospital Regensburg, 93053 Regensburg, Germany.ORCID 0000-0001-8781-8187
Martin TrepelBavarian Center for Cancer Research (BZKF), 91054 Erlangen, Germany.
Matthias EvertComprehensive Cancer Center Ostbayern, 93053 Regensburg, Germany.
Rainer ClausMedical Faculty, Institute of Pathology and Molecular Diagnostics, University of Augsburg, 86156 Augsburg, Germany.ORCID 0000-0003-2617-8766
Alexander KerscherComprehensive Cancer Center Mainfranken, University Hospital Würzburg, 97080 Würzburg, Germany.ORCID 0000-0001-7742-570X
Comprehensive Cancer Center Mainfranken · DEUniversity Hospital Regensburg · DEUniversity of Augsburg · DEUniversity of Regensburg · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversitätsklinikum Erlangen · DEUniversity of Würzburg · DEUniversitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: molecular tumor boards (MTBs) are crucial instruments for discussing and allocating targeted therapies to suitable cancer patients based on genetic findings. Currently, limited evidence is available regarding the regional impact and the outreach component of MTBs; (2) Methods: we analyzed MTB patient data from four neighboring Bavarian tertiary care oncology centers in Würzburg, Erlangen, Regensburg, and Augsburg, together constituting the WERA Alliance. Absolute patient numbers and regional distribution across the WERA-wide catchment area were weighted with local population densities; (3) Results: the highest MTB patient numbers were found close to the four cancer centers. However, peaks in absolute patient numbers were also detected in more distant and rural areas. Moreover, weighting absolute numbers with local population density allowed for identifying so-called white spots-regions within our catchment that were relatively underrepresented in WERA MTBs; (4) Conclusions: investigating patient data from four neighboring cancer centers, we comprehensively assessed the regional impact of our MTBs. The results confirmed the success of existing collaborative structures with our regional partners. Additionally, our results help identifying potential white spots in providing precision oncology and help establishing a joint WERA-wide outreach strategy.

Indexed as

cancer careMTBoutcomes researchoutreachpatient accessprecision oncologyreal world data

Identifiers

PMID36291825
PMCPMC9600149
OpenAlexW4306366859

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.