Evidence map›Paper›PMID 36291800›Full record

ArticleCancers2022

Measurement Accuracy and Repeatability of RECIST-Defined Pulmonary Lesions and Lymph Nodes in Ultra-Low-Dose CT Based on Deep Learning Image Reconstruction.

Keke Zhao, Beibei Jiang, Shuai Zhang, Lu Zhang, Lin Zhang, Yan Feng, Jianying Li, Yaping Zhang, Xueqian Xie

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Keke ZhaoRadiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Rd.100, Shanghai 200080, China.
Beibei JiangRadiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Rd.100, Shanghai 200080, China.
Shuai ZhangCT Imaging Research Center, GE Healthcare China, Shanghai 201203, China.
Lu ZhangRadiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Rd.100, Shanghai 200080, China.
Lin ZhangRadiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Rd.100, Shanghai 200080, China.
Yan FengRadiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Rd.100, Shanghai 200080, China.
Jianying LiCT Imaging Research Center, GE Healthcare China, Shanghai 201203, China.
Yaping ZhangRadiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Rd.100, Shanghai 200080, China.
Xueqian XieRadiology Department, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Haining Rd.100, Shanghai 200080, China.ORCID 0000-0002-6669-0097
Shanghai Jiao Tong University · CNUnited Imaging Healthcare (China) · CN

Funding

Ministry of Science and Technology of China 2016YFE0103000National Natural Science Foundation of China 81971612 and 81471662Shanghai Jiao Tong University ZH2018ZDB10
6 · The paper itself

Abstract

backgroundDeep learning image reconstruction (DLIR) improves image quality. We aimed to compare the measured diameter of pulmonary lesions and lymph nodes between DLIR-based ultra-low-dose CT (ULDCT) and contrast-enhanced CT.

methodsThe consecutive adult patients with noncontrast chest ULDCT (0.07-0.14 mSv) and contrast-enhanced CT (2.38 mSv) were prospectively enrolled. Patients with poor image quality and body mass index ≥ 30 kg/m

resultsThe 141 enrolled patients (62 ± 12 years) had 89 RECIST-defined measurable pulmonary target lesions (including 30 malignant lesions, mainly adenocarcinomas) and 45 measurable mediastinal lymph nodes (12 malignant). The measurement variation of pulmonary lesions between high-strength DLIR (DLIR-H) images of ULDCT and contrast-enhanced CT was 2.2% (95% CI: 1.7% to 2.6%) and the variation of lymph nodes was 1.4% (1.0% to 1.9%).

conclusionsThe measured diameters of pulmonary lesions and lymph nodes in DLIR-H images of ULDCT are highly close to those of contrast-enhanced CT. DLIR-based ULDCT may facilitate evaluating target lesions with greatly reduced radiation exposure in tumor evaluation and lung cancer screening.

Indexed as

artificial intelligencecomputed tomographydimensional measurement accuracylung cancerpulmonary noduleResponse Evaluation Criteria in Solid Tumors

Identifiers

PMID36291800
PMCPMC9599467
OpenAlexW4306149433

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.