Evidence map›Paper›PMID 36291599›Full record

ReviewBiomolecules2022

Use of Visual Electrophysiology to Monitor Retinal and Optic Nerve Toxicity.

Tsun-Kang Chiang, Kayla Marie White, Shree K Kurup, Minzhong Yu

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Measuring electroretinograms in tree shrews with a portable electrophysiology device.Documenta ophthalmologica. Advances in ophthalmology · 2026
    Article
  2. Severe visual impairment as a complication of autism spectrum disorder.Documenta ophthalmologica. Advances in ophthalmology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tsun-Kang ChiangUniversity Hospitals Eye Institute, Case Western Reserve University, Cleveland, OH 44101, USA.ORCID 0000-0002-1400-135X
Kayla Marie WhiteUniversity Hospitals Eye Institute, Case Western Reserve University, Cleveland, OH 44101, USA.
Shree K KurupUniversity Hospitals Eye Institute, Case Western Reserve University, Cleveland, OH 44101, USA.
Minzhong YuUniversity Hospitals Eye Institute, Case Western Reserve University, Cleveland, OH 44101, USA.ORCID 0000-0002-3115-8930
Case Western Reserve University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is important for clinicians to consider exposure to toxic substances and nutritional deficiencies when diagnosing and managing cases of vision loss. In these cases, physiologic damage can alter the function of key components of the visual pathway before morphologic changes can be detected by traditional imaging methods. Electrophysiologic tests can aid in the early detection of such functional changes to visual pathway components, including the retina or optic nerve. This review provides an overview of various electrophysiologic techniques, including multifocal electroretinogram (mfERG), full-field ERG (ffERG), electrooculogram (EOG), pattern electroretinogram (PERG), and visual evoked potential (VEP) in monitoring the retinal and optic nerve toxicities of alcohol, amiodarone, cefuroxime, cisplatin, deferoxamine, digoxin, ethambutol, hydroxychloroquine, isotretinoin, ocular siderosis, pentosane, PDE5 inhibitors, phenothiazines (chlorpromazine and thioridazine), quinine, tamoxifen, topiramate, vigabatrin, and vitamin A deficiency.

Indexed as

AmiodaroneEvoked Potentials, VisualCefuroximeChlorpromazineCisplatinDeferoxamineDigoxinElectrophysiologyEthambutolHumansHydroxychloroquineIsotretinoinOptic NervePhosphodiesterase 5 InhibitorsQuinineRetinaAmiodaroneCefuroximeChlorpromazineCisplatinDeferoxamineDigoxinEthambutolHydroxychloroquineIsotretinoinPhosphodiesterase 5 InhibitorsQuinineTamoxifenThioridazineTopiramateVigabatrindrugelectrooculogramelectrophysiologyelectroretinogrameyefunctional examoptic nerveretinatoxicityvisual evoked potential

Identifiers

PMID36291599
PMCPMC9599231
OpenAlexW4297982511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.