Evidence map›Paper›PMID 36291550›Full record

ReviewBiomolecules2022

Ractopamine at the Center of Decades-Long Scientific and Legal Disputes: A Lesson on Benefits, Safety Issues, and Conflicts.

Kumail Abbas, Aqeel Raza, Ross D Vasquez, Marri Jmelou M Roldan, Nemi Malhotra, Jong-Chin Huang, Olivia E M Buenafe, Kelvin H-C Chen, Shih-Shin Liang, Chung-Der Hsiao

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Kumail AbbasDepartment of Bioscience Technology, Chung Yuan Christian University, Taoyuan 320314, Taiwan.ORCID 0000-0003-4055-0915
Aqeel RazaDepartment of Veterinary Medicine, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.ORCID 0000-0002-0306-6967
Ross D VasquezResearch Center for the Natural and Applied Sciences, University of Santo Tomas, Manila 1015, Philippines.ORCID 0000-0002-5906-9710
Marri Jmelou M RoldanThe Graduate School, University of Santo Tomas, Manila 1015, Philippines.ORCID 0000-0001-6398-1828
Nemi MalhotraDepartment of Bioscience Technology, Chung Yuan Christian University, Taoyuan 320314, Taiwan.
Jong-Chin HuangDepartment of Applied Chemistry, National Pingtung University, Pingtung 900391, Taiwan.ORCID 0000-0003-3997-1683
Olivia E M BuenafeDepartment of Chemistry, Ateneo de Manila University, Katipunan Ave., Loyola Heights, Quezon City 1108, Philippines.ORCID 0000-0001-6048-4121
Kelvin H-C ChenDepartment of Applied Chemistry, National Pingtung University, Pingtung 900391, Taiwan.ORCID 0000-0002-2709-2633
Shih-Shin LiangDepartment of Biotechnology, College of Life Science, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0003-1437-177X
Chung-Der HsiaoDepartment of Bioscience Technology, Chung Yuan Christian University, Taoyuan 320314, Taiwan.ORCID 0000-0002-6398-8672
Chung Yuan Christian University · TWNational Pingtung University · TWUniversity of Santo Tomas · PHAteneo de Manila University · PHChulalongkorn University · THNational Sun Yat-sen University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ractopamine (RAC) is a synthetic phenethanolamine, β-adrenergic agonist used as a feed additive to develop leanness and increase feed conversion efficiency in different farm animals. While RAC has been authorized as a feed additive for pigs and cattle in a limited number of countries, a great majority of jurisdictions, including the European Union (EU), China, Russia, and Taiwan, have banned its use on safety grounds. RAC has been under long scientific and political discussion as a controversial antibiotic as a feed additive. Here, we will present significant information on RAC regarding its application, detection methods, conflicts, and legal divisions that play a major role in controversial deadlock and why this issue warrants the attention of scientists, agriculturists, environmentalists, and health advocates. In this review, we highlight the potential toxicities of RAC on aquatic animals to emphasize scientific evidence and reports on the potentially harmful effects of RAC on the aquatic environment and human health.

Indexed as

Animal FeedDissent and DisputesAdrenergic beta-AgonistsAnimalsAnti-Bacterial AgentsCattleHumansPhenethylaminesSwineAdrenergic beta-AgonistsAnti-Bacterial AgentsPhenethylaminesractopamineaquatic animalsfeed additiveractopaminetoxicity

Identifiers

PMID36291550
PMCPMC9599871
OpenAlexW4296897618

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.