Evidence map›Paper›PMID 36291458›Full record

ArticleChildren (Basel, Switzerland)2022

Preterm ETs Are Significantly Reduced Compared with Adults and Partially Reduced Compared with Term Infants.

Aila Wirkner, Antje Vogelgesang, Ines Hegge, Anja Lange, Dirk Manfred Olbertz, Bernd Gerber, Matthias Heckmann, Johanna Ruhnau

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Aila WirknerDepartment of Neonatology and Pediatric Intensive Care, University Medicine Greifswald, 17475 Greifswald, Germany.
Antje VogelgesangDepartment of Neurology, University Medicine Greifswald, 17475 Greifswald, Germany.ORCID 0000-0003-2984-0831
Ines HeggeDepartment of Neonatology and Pediatric Intensive Care, University Medicine Greifswald, 17475 Greifswald, Germany.
Anja LangeDepartment of Neonatology and Pediatric Intensive Care, University Medicine Greifswald, 17475 Greifswald, Germany.
Dirk Manfred OlbertzDepartment of Neonatology, South Clinic, University Rostock, 18059 Rostock, Germany.
Bernd GerberDepartment of Obstetrics and Gynecology, South Clinic, University Rostock, 18059 Rostock, Germany.
Matthias HeckmannDepartment of Neonatology and Pediatric Intensive Care, University Medicine Greifswald, 17475 Greifswald, Germany.ORCID 0000-0002-5260-264X
Johanna RuhnauDepartment of Neurology, University Medicine Greifswald, 17475 Greifswald, Germany.ORCID 0000-0003-0238-1305
Universitätsmedizin Greifswald · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The release of DNA by cells during extracellular trap (ET) formation is a defense function of neutrophils and monocytes. Neutrophil ET (NET) formation in term infants is reduced compared to adults. Objective: The aim was to quantify NET and monocyte ET (MET) release and the respective key enzymes myeloperoxidase (MPO) and neutrophil elastase (NE) in preterm infants. In this prospective explorative study, ET induction was stimulated by N-formylmethionine-leucyl-phenylalanine (fMLP), phorbol 12-myristate 13-acetate (PMA), lipopolysaccharide (LPS), and lipoteichoic acid (LTA) in the cord blood of preterm infants (

Indexed as

extracellular trapsmonocytesneutrophilspreterm infant

Identifiers

PMID36291458
PMCPMC9600659
OpenAlexW4303629017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.