ArticleChildren (Basel, Switzerland)2022
Gingival Margins' Modifications during Orthodontic Treatment with Invisalign First
Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of clear aligners treatment in growing patients: a systematic review.Frontiers in oral health · 2024Pooled it
- Management of Skeletal Class II Malocclusion in a Growing Patient Using Clear Aligners and Class II Elastics: A Case Report.Dentistry journal · 2026Article
- Skeletal and Dental-Alveolar Changes With Invisalign First Expansion System in the Mixed Dentition: A Retrospective Study.Orthodontics & craniofacial research · 2026Article
- Occlusal Relationships and Dental Changes in Mixed Dentition Patients Treated with Clear Aligners: A 2-Year Follow Up.Children (Basel, Switzerland) · 2026Article
- Severe Crowding Associated with Lower Canine Premature Resorption: Interceptive Treatment with Clear Aligners-A Pilot Study.Children (Basel, Switzerland) · 2024Article
- Clear Aligners in the Growing Patient: A Systematic Review.Children (Basel, Switzerland) · 2024Review
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the study was to assess modifications of gingival morphology at the end of Phase I treatment with Invisalign First. Eighteen subjects (ten females, eight males, mean age nine years) treated with Invisalign First were selected. The following parameters were measured on intraoral photographs before treatment (T0) and after the first set of aligners (T1) at level of permanent incisors, deciduous canines and molars: gingival margin height (GMH) and deciduous canine inclination (DCI). A paired t-test was used to evaluate T1-T0 changes. The level of significance was established at 5%. Deciduous canines' GMH showed a major reduction between T1 and T0 accounting for 0.87 mm and 0.86 mm, respectively on the right and left sides. DCI increased for all patients in the interval T0-T1 on both sides, +7.11° on the right and +7.5° on the left. Tooth movement during Invisalign First induced significant modifications of gingival contour resulting in a more harmonious smile.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.