Evidence map›Paper›PMID 36291347›Full record

ArticleBrain sciences2022

Investigating p62 Concentrations in Cerebrospinal Fluid of Patients with Dementia: A Potential Autophagy Biomarker In Vivo?

Elisa Rubino, Silvia Boschi, Fausto Roveta, Andrea Marcinnò, Aurora Cermelli, Cristina Borghese, Maria Claudia Vigliani, Innocenzo Rainero

Abstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Survival in sporadic ALS is associated with lower p62 burden in the spinal cord.Journal of neuropathology and experimental neurology · 2023
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elisa RubinoDepartment of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, 10126 Torino, Italy.
Silvia BoschiDepartment of Neuroscience "Rita Levi Montalcini", University of Torino, 10126 Torino, Italy.ORCID 0000-0003-1610-1917
Fausto RovetaDepartment of Neuroscience "Rita Levi Montalcini", University of Torino, 10126 Torino, Italy.
Andrea MarcinnòDepartment of Neuroscience "Rita Levi Montalcini", University of Torino, 10126 Torino, Italy.
Aurora CermelliDepartment of Neuroscience "Rita Levi Montalcini", University of Torino, 10126 Torino, Italy.ORCID 0000-0001-9753-9288
Cristina BorgheseDepartment of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, 10126 Torino, Italy.
Maria Claudia ViglianiDepartment of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, 10126 Torino, Italy.
Innocenzo RaineroDepartment of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, 10126 Torino, Italy.ORCID 0000-0001-6074-9628

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have revealed defects in autophagy in neurodegenerative disorders including Alzheimer's disease (AD) and frontotemporal dementia (FTD).

Indexed as

Alzheimer’s diseaseautophagybiomarkerscerebrospinal fluidfrontotemporal dementiaSQSTM1/p62

Identifiers

PMID36291347
PMCPMC9599226

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.