ReviewBrain sciences2022
Postoperative Delirium in Neurosurgical Patients: Recent Insights into the Pathogenesis.
Review in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Effect of preoperative oral carbohydrate on postoperative delirium in elderly patients undergoing lower extremity orthopedic surgery: a prospective randomized trial.Journal of orthopaedic surgery and research · 2025Trial
- Reconsidering Surgical Intervention for Infection After Cranioplasty in Older Adults: A Case Report.Cureus · 2026Article
- Association between the unaccompanied nursing care model and postoperative delirium in older adults with hip fractures: a retrospective before-and-after cohort study.Frontiers in medicine · 2026Article
- Association of multidisciplinary collaborative nursing with cognitive function and quality of life after craniotomy for glioma resection: a retrospective comparative study.Frontiers in medicine · 2026Article
- Neuroprotective mechanisms of dexmedetomidine in perioperative neurocognitive disorders: From molecular pathways to clinical translation.Journal of anesthesia and translational medicine · 2025Review
- The Relationship Between the Average Infusion Rate of Propofol and the Incidence of Delirium During Invasive Mechanical Ventilation: A Retrospective Study Based on the MIMIC IV Database.CNS neuroscience & therapeutics · 2025Article
- Correlation of β2-microglobulin with postoperative delirium and 3-year mortality undergoing knee or hip replacement surgery: a prospective cohort study.Frontiers in medicine · 2025Article
- Comprehensive Geriatric Assessment as a predictor model for post-operative delirium in older adults undergoing major non-cardiac elective surgery.Frontiers in medicine · 2025Article
- Article
- AI-Assisted Identification of Primary and Secondary Metabolomic Markers for Postoperative Delirium.International journal of molecular sciences · 2024Article
- Association of preoperative frailty with risk of postoperative delirium in older patients undergoing craniotomy: a prospective cohort study.BMC surgery · 2024Article
- Review
- Correlation analysis between plasma biomarkers albumin, fibrinogen, and their ratio with postoperative delirium in patients undergoing non-cardiac surgery: a systematic review and meta-analysis.American journal of translational research · 2024Review
- The Association of Infection with Delirium in the Post-Operative Period after Elective CABG Surgery.Journal of clinical medicine · 2023Article
- Transcutaneous Electrical Acupoint Stimulation for Preventing Postoperative Delirium: A Meta-Analysis.Neuropsychiatric disease and treatment · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Postoperative delirium (POD) is a complication characterized by disturbances in attention, awareness, and cognitive function that occur shortly after surgery or emergence from anesthesia. Since it occurs prevalently in neurosurgical patients and poses great threats to the well-being of patients, much emphasis is placed on POD in neurosurgical units. However, there are intricate theories about its pathogenesis and limited pharmacological interventions for POD. In this study, we review the recent insights into its pathogenesis, mainly based on studies within five years, and the five dominant pathological theories that account for the development of POD, with the intention of furthering our understanding and boosting its clinical management.
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