ArticleBrain sciences2022
Analysis of Influencing Factors of Apathy in Patients with Parkinson's Disease.
Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- Apathy in Parkinson's Disease: Distinguishing Overlapping Symptoms Via Network Analysis.Movement disorders clinical practice · 2026Article
- Network localization of functional and structural correlates of apathy in Parkinson's disease.Frontiers in systems neuroscience · 2026Article
- Adaptation of the Caregiver Version of the Starkstein Apathy Scale (SAS) into Turkish and Investigation of Its Reliability and Validity in Parkinson's Disease.Noro psikiyatri arsivi · 2026Article
- Participation of ethnic minorities in Parkinson's research: challenges and needs. A qualitative study.Age and ageing · 2025Article
- Interpretable Machine Learning for Cross-Cohort Prediction of Motor Fluctuations in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- Review
- Multiple sleep disturbances are associated with apathy in individuals with Parkinson's disease.Heliyon · 2024Article
- The Impact of Fatigue on Sleep and Other Non-Motor Symptoms in Parkinson's Disease.Brain sciences · 2024Article
- Treatment of Apathy in Parkinson's Disease and Implications for Underlying Pathophysiology.Journal of clinical medicine · 2024Review
- Prevalence and Influencing Factors of Depression in Patients with Parkinson's Disease.Alpha psychiatry · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundApathy is a common non-motor symptom of Parkinson's disease (PD). The influencing factors of apathy are currently controversial. This study aimed to describe the clinical characteristics of PD-associated apathy and to analyze the associated risk factors.
methodsTwo hundred patients diagnosed with PD were selected. Included patients were divided into an apathetic group and a non-apathetic group. Demographic and clinical data, motor symptoms, non-motor symptoms and medication use of the two groups were assessed.
resultsThe incidence of apathy was 69%. Demographic and clinical data, motor symptoms, non-motor symptoms and medications use were statistically significant.
conclusionsPD patients with more severe motor symptoms, cognitive impairment, depression, anxiety, RBD, excessive daytime sleep, fatigue, low education level, long disease course, poor quality of life and lower DA dosage are more prone to apathy. Cognitive function, quality of life, educational level, DA and LEDD are independent risk factors for apathy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.