Evidence map›Paper›PMID 36291250›Full record

ArticleBrain sciences2022

Neuroticism and Conscientiousness Moderate the Effect of Oral Medication Beliefs on Adherence of People with Mental Illness during the Pandemic.

Fabio Ferretti, Arianna Goracci, Pier Francesco Laurenzi, Rossella Centola, Irene Crecchi, Aldo De Luca, Janette Monzillo, Omar Guidi, Giusy Sinigaglia, Giacomo Gualtieri and 7 more

Abstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Therapeutic Adherence of People with Mental Disorders: An Evolutionary Concept Analysis.International journal of environmental research and public health · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Fabio FerrettiDepartment of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Arianna GoracciDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, Italy.
Pier Francesco LaurenziDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, Italy.ORCID 0000-0002-7455-7755
Rossella CentolaUOC Farmacia, AOU San Giovanni di Dio e Ruggi d'Aragona, 84131 Salerno, Italy.ORCID 0000-0002-9580-2107
Irene CrecchiUOC Farmacia Ospedaliera, Azienda Ospedaliera Universitaria Senese, 53100 Siena, Italy.
Aldo De LucaFarmacia, Istituto Nazionale Malattie Infettive "L. Spallanzani" IRCCS, 00149 Rome, Italy.
Janette MonzilloScuola di Specializzazione in Farmacia Ospedaliera, University of Siena, 53100 Siena, Italy.
Omar GuidiScuola di Specializzazione in Farmacia Ospedaliera, University of Siena, 53100 Siena, Italy.
Giusy SinigagliaScuola di Specializzazione in Farmacia Ospedaliera, University of Siena, 53100 Siena, Italy.
Giacomo GualtieriDepartment of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Lore LorenziDepartment of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Alessandro CuomoDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, Italy.
Simone BolognesiDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, Italy.
Valter TravagliUOC Farmacia Ospedaliera, Azienda Ospedaliera Universitaria Senese, 53100 Siena, Italy.ORCID 0000-0002-7574-4456
Anna ColucciaDepartment of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Andrea FagioliniDepartment of Molecular Medicine, School of Medicine, University of Siena, 53100 Siena, Italy.
Andrea PozzaDepartment of Medical Sciences, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAfter the declaration of the pandemic status in several countries, the continuity of face-to-face visits in psychiatric facilities has been delayed or even interrupted to reduce viral spread. Little is known about the personality factors associated with medication beliefs and adherence amongst individuals with mental illness during the COVID-19 pandemic. This brief report describes a preliminary naturalistic longitudinal study that explored whether the Big Five personality traits prospectively moderate the effects of medication beliefs on changes in adherence during the pandemic for a group of outpatients with psychosis or bipolar disorder.

methodsThirteen outpatients undergoing routine face-to-face follow-up assessments during the pandemic were included (41 observations overall) and completed the Revised Italian Version of the Ten-Item Personality Inventory, the Beliefs about Medicines Questionnaire, the Morisky Medication Adherence Scale-8-item and the Beck Depression Inventory-II.

resultsParticipants had stronger concerns about their psychiatric medications rather than beliefs about their necessity, and adherence to medications was generally low. Participants who had more necessity beliefs than concerns had better adherence to medications. People scoring higher in Conscientiousness and Neuroticism traits and more concerned about the medication side effects had poorer adherence.

conclusionsThese preliminary data suggest the importance of a careful assessment of the adherence to medications amongst people with psychosis/bipolar disorder during the pandemic. Interventions aimed to improve adherence might focus on patients' medication beliefs and their Conscientiousness and Neuroticism personality traits.

Indexed as

adherencebeliefs about medicationsBig Five personalityCOVID-19 pandemicmental disordersstress

Identifiers

PMID36291250
PMCPMC9599797

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.