Evidence map›Paper›PMID 36291243›Full record

ArticleBrain sciences2022

An Exploratory Study of a Novel Combined Therapeutic Modality for Obsessive-Compulsive Disorder.

Yueqi Huang, Hangyi Yang, Cheng Zhu, Xiaoying Jiang, Wenjing Zhu, Yan Liang, Lisha Ma, Yunzan Wang, Wenxin Tang

Abstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yueqi HuangDepartment of Psychiatry, Affiliated Mental Health Centre and Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou 310013, China.ORCID 0000-0003-2917-1578
Hangyi YangFourth Clinical School, Zhejiang Chinese Medical University, Hangzhou 310013, China.ORCID 0000-0002-2988-1724
Cheng ZhuDepartment of Psychiatry, Affiliated Mental Health Centre and Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou 310013, China.
Xiaoying JiangDepartment of Psychiatry, Affiliated Mental Health Centre and Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou 310013, China.
Wenjing ZhuDepartment of Psychiatry, Affiliated Mental Health Centre and Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou 310013, China.
Yan LiangDepartment of Psychiatry, Affiliated Mental Health Centre and Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou 310013, China.
Lisha MaDepartment of Psychiatry, Affiliated Mental Health Centre and Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou 310013, China.
Yunzan WangDepartment of Psychiatry, Affiliated Mental Health Centre and Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou 310013, China.
Wenxin TangDepartment of Psychiatry, Affiliated Mental Health Centre and Hangzhou Seventh People's Hospital, Zhejiang University School of Medicine, Hangzhou 310013, China.

Funding

Medical Health Science and Technology Project of Zhejiang Provincial Health Commission 2022KY993Zhejiang Provincial Natural Science Foundation of China under Grant LGF19H090015
6 · The paper itself

Abstract

objectiveTo explore whether a systematic combined therapeutic modality (CTM) could quickly and effectively improve the severity of obsessive-compulsive disorder (OCD) and the insight of OCD patients.

methodsIncluded in this study were 100 patients with OCD according to the 5th Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), for a 2-week short-term treatment. They were assigned to a drug-alone group (

resultsAfter the 2-week treatment, the success rate in the CTM group was significantly higher than that in the drug-alone group. Y-BOCS overall and factor scores were decreased as compared with those before treatment in both groups. HAMD, HAMA and BABS overall scores were all decreased after treatment in the CTM group. In addition, compared with the drug-alone group, the Y-BOCS overall score and factor score, HAMD overall score and HAMA overall score were all decreased significantly in CTM group, while the Y-BOCS score reduction rate was increased significantly. Insight was improved in eight cases (57.14%) in the CTM group containing 14 cases with poor insight. Multinomial logistic regression analysis showed that CTM was beneficial for the insight improvement of OCD patients (OR = 91.04-139.68); this improvement was more pronounced in patients with low baseline BABS overall scores (OR = 0.07).

conclusionCTM may be an effective short-term strategy to improve the severity of OCD and insight of OCD patients and, therefore, is worthy of clinical promotion and application.

Indexed as

cognitive behavioral therapycombined therapeutic modalityinsightobsessive–compulsive disorderrepetitive transcranial magnetic stimulation

Identifiers

PMID36291243
PMCPMC9599080

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.