Evidence map›Paper›PMID 36291093›Full record

ArticleCells2022

Reduction in SOCE and Associated Aggregation in Platelets from Mice with Platelet-Specific Deletion of Orai1.

Linlin Yang, Roger Ottenheijm, Paul Worley, Marc Freichel, Juan E Camacho Londoño

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Physiological functions of calcium signaling via Orai1 in cancer.The journal of physiological sciences : JPS · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Linlin YangPharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.
Roger OttenheijmPharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.ORCID 0000-0003-2137-6173
Paul WorleyThe Solomon H. Snyder Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA.
Marc FreichelPharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.ORCID 0000-0003-1387-2636
Juan E Camacho LondoñoPharmakologisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 366, 69120 Heidelberg, Germany.ORCID 0000-0003-0673-7583
Heidelberg University · DEJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium signalling in platelets through store operated Ca

Indexed as

Blood PlateletsCalciumORAI1 Protein15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidAdenosine DiphosphateAdenosine TriphosphatasesAnimalsCalcium ChannelsCalcium SignalingCollagenFemaleMaleMicePeptidesStromal Interaction Molecule 1Thapsigargin15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidAdenosine DiphosphateAdenosine TriphosphatasesCalciumCalcium ChannelsCollagenORAI1 ProteinOrai1 protein, mousePeptidesStromal Interaction Molecule 1ThapsigarginThrombinThromboxane A2calcium signallingOrai1 proteinsplatelet aggregationplatelet specific knockout micereceptor-operated Ca2+ entry (ROCE)store operated Ca2+ entry (SOCE)

Identifiers

PMID36291093
PMCPMC9600098
OpenAlexW4306366820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.