Evidence map›Paper›PMID 36290928›Full record

ArticleBiosensors2022

Staging of Skin Cancer Based on Hyperspectral Microscopic Imaging and Machine Learning.

Lixin Liu, Meijie Qi, Yanru Li, Yujie Liu, Xing Liu, Zhoufeng Zhang, Junle Qu

Abstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lixin LiuSchool of Optoelectronic Engineering, Xidian University, Xi'an 710071, China.
Meijie QiSchool of Optoelectronic Engineering, Xidian University, Xi'an 710071, China.ORCID 0000-0002-2264-7572
Yanru LiSchool of Optoelectronic Engineering, Xidian University, Xi'an 710071, China.
Yujie LiuSchool of Optoelectronic Engineering, Xidian University, Xi'an 710071, China.
Xing LiuSino-German College of Intelligent Manufacturing, Shenzhen Technology University, Shenzhen 518118, China.
Zhoufeng ZhangCAS Key Laboratory of Spectral Imaging Technology, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an 710119, China.
Junle QuCollege of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China.ORCID 0000-0001-7833-4711

Funding

CAS Key Laboratory of Spectral Imaging Technology LSIT202005WDepartment of Science and Technology of Shaanxi Province 2020JQ-204Shenzhen Technology University GDRC202106
6 · The paper itself

Abstract

Skin cancer, a common type of cancer, is generally divided into basal cell carcinoma (BCC), squamous cell carcinoma (SCC) and malignant melanoma (MM). The incidence of skin cancer has continued to increase worldwide in recent years. Early detection can greatly reduce its morbidity and mortality. Hyperspectral microscopic imaging (HMI) technology can be used as a powerful tool for skin cancer diagnosis by reflecting the changes in the physical structure and microenvironment of the sample through the differences in the HMI data cube. Based on spectral data, this work studied the staging identification of SCC and the influence of the selected region of interest (ROI) on the staging results. In the SCC staging identification process, the optimal result corresponded to the standard normal variate transformation (SNV) for spectra preprocessing, the partial least squares (PLS) for dimensionality reduction, the hold-out method for dataset partition and the random forest (RF) model for staging identification, with the highest staging accuracy of 0.952 ± 0.014, and a kappa value of 0.928 ± 0.022. By comparing the staging results based on spectral characteristics from the nuclear compartments and peripheral regions, the spectral data of the nuclear compartments were found to contribute more to the accurate staging of SCC.

Indexed as

Basal Cell CarcinomaCarcinoma, Squamous CellMelanomaSkin NeoplasmsHumansLeast-Squares AnalysisMachine LearningTumor Microenvironmentcancer classificationhyperspectral microscopic imaging technologymachine learningskin cancerstaging identification

Identifiers

PMID36290928
PMCPMC9599813

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.