Evidence map›Paper›PMID 36290927›Full record

ReviewBiosensors2022

Biosensors and Drug Delivery in Oncotheranostics Using Inorganic Synthetic and Biogenic Magnetic Nanoparticles.

Tatiana M Zimina, Nikita O Sitkov, Kamil G Gareev, Viacheslav Fedorov, Denis Grouzdev, Veronika Koziaeva, Huile Gao, Stephanie E Combs, Maxim Shevtsov

Abstract readReview
In one paragraph

Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
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  4. Effects of ZnFeToxics · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tatiana M ZiminaDepartment of Micro and Nanoelectronics, Saint Petersburg Electrotechnical University "LETI", 197022 Saint Petersburg, Russia.
Nikita O SitkovDepartment of Micro and Nanoelectronics, Saint Petersburg Electrotechnical University "LETI", 197022 Saint Petersburg, Russia.ORCID 0000-0003-4870-8641
Kamil G GareevDepartment of Micro and Nanoelectronics, Saint Petersburg Electrotechnical University "LETI", 197022 Saint Petersburg, Russia.ORCID 0000-0001-6047-1208
Viacheslav FedorovLaboratory of Biomedical Nanotechnologies, Institute of Cytology of the Russian Academy of Sciences, 194064 Saint Petersburg, Russia.ORCID 0000-0002-0239-7473
Denis GrouzdevSciBear OU, Tartu mnt 67/1-13b, Kesklinna Linnaosa, 10115 Tallinn, Estonia.ORCID 0000-0002-1358-5146
Veronika KoziaevaLaboratory of Biomedical Nanotechnologies, Institute of Cytology of the Russian Academy of Sciences, 194064 Saint Petersburg, Russia.ORCID 0000-0002-6000-8886
Huile GaoKey Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China.ORCID 0000-0002-5355-7238
Stephanie E CombsDepartment of Radiation Oncology, Klinikum Rechts der Isar, Technical University of Munich, 81675 Munich, Germany.
Maxim ShevtsovLaboratory of Biomedical Nanotechnologies, Institute of Cytology of the Russian Academy of Sciences, 194064 Saint Petersburg, Russia.

Funding

National Natural Science Foundation of China 81961138009Russian Science Foundation 22-15-00240
6 · The paper itself

Abstract

Magnetic nanocarriers have attracted attention in translational oncology due to their ability to be employed both for tumor diagnostics and therapy. This review summarizes data on applications of synthetic and biogenic magnetic nanoparticles (MNPs) in oncological theranostics and related areas. The basics of both types of MNPs including synthesis approaches, structure, and physicochemical properties are discussed. The properties of synthetic MNPs and biogenic MNPs are compared with regard to their antitumor therapeutic efficiency, diagnostic potential, biocompatibility, and cellular toxicity. The comparative analysis demonstrates that both synthetic and biogenic MNPs could be efficiently used for cancer theranostics, including biosensorics and drug delivery. At the same time, reduced toxicity of biogenic particles was noted, which makes them advantageous for in vivo applications, such as drug delivery, or MRI imaging of tumors. Adaptability to surface modification based on natural biochemical processes is also noted, as well as good compatibility with tumor cells and proliferation in them. Advances in the bionanotechnology field should lead to the implementation of MNPs in clinical trials.

Indexed as

Biosensing TechniquesMagnetite NanoparticlesNanoparticlesNeoplasmsDrug Delivery SystemsHumansMagnetic Resonance ImagingMagneticsMagnetite Nanoparticlesbiogenic magnetic nanoparticlesbiosensorsdrug deliverymagnetic nanoparticlesmagnetosomesmagnetotactic bacteriaoncotheranostics

Identifiers

PMID36290927
PMCPMC9599632

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.