Evidence map›Paper›PMID 36290918›Full record

ReviewBiosensors2022

Detection of Alpha-Fetoprotein Using Aptamer-Based Sensors.

Lei Liu, Huixing Wang, Bing Xie, Bianjiang Zhang, Yuanwei Lin, Li Gao

Abstract readReview
In one paragraph

Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Nanotechnology for the Diagnosis and Treatment of Liver Cancer.International journal of nanomedicine · 2024
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lei LiuDepartment of Kidney Transplantation, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
Huixing WangSchool of Life Sciences, Jiangsu University, Zhenjiang 212013, China.
Bing XieDepartment of Obstetrics and Gynecology, The Fourth People's Hospital of Zhenjiang, Zhenjiang 212000, China.
Bianjiang ZhangSchool of Food Science, Nanjing Xiaozhuang University, Nanjing 211171, China.
Yuanwei LinSchool of Life Sciences, Jiangsu University, Zhenjiang 212013, China.ORCID 0000-0002-5293-1777
Li GaoSchool of Life Sciences, Jiangsu University, Zhenjiang 212013, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alpha-fetoprotein (AFP) is widely-known as the most commonly used protein biomarker for liver cancer diagnosis at the early stage. Therefore, developing the highly sensitive and reliable method of AFP detection is of essential demand for practical applications. Herein, two types of aptamer-based AFP detection methods, i.e., optical and electrochemical biosensors, are reviewed in detail. The optical biosensors include Raman spectroscopy, dual-polarization interferometry, resonance light-scattering, fluorescence, and chemiluminescence. The electrochemical biosensors include cyclic voltammetry, electrochemical impedance spectroscopy, and giant magnetic impedance. Looking into the future, methods for AFP detection that are high sensitivity, long-term stability, low cost, and operation convenience will continue to be developed.

Indexed as

Aptamers, NucleotideBiosensing Techniquesalpha-FetoproteinsElectrochemical TechniquesLimit of Detectionalpha-FetoproteinsAptamers, NucleotideAlpha-fetoproteinaptamerdetectionelectrochemical biosensorsoptical biosensors

Identifiers

PMID36290918
PMCPMC9599106

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.