Evidence map›Paper›PMID 36290905›Full record

Trial reportCurrent oncology (Toronto, Ont.)2022

Sleep Disturbance Affects Immune Factors in Clinical Liver Cancer Patients.

Zuoyun Wang, Yan Wang, Jing Huang, Jietian Xu, Fangzhen Chen, Zidan Zhu, Lingling Gao, Jie Qin, Binbin Liu, Chunmin Liang

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Zuoyun WangLaboratory of Tumor Immunology, Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences and Jing'an District Central Hospital of Shanghai, Shanghai Medical College, Fudan University, Shanghai 200030, China.ORCID 0000-0003-4428-5477
Yan WangLiver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200030, China.
Jing HuangLaboratory of Tumor Immunology, Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences and Jing'an District Central Hospital of Shanghai, Shanghai Medical College, Fudan University, Shanghai 200030, China.
Jietian XuLaboratory of Tumor Immunology, Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences and Jing'an District Central Hospital of Shanghai, Shanghai Medical College, Fudan University, Shanghai 200030, China.
Fangzhen ChenLaboratory of Tumor Immunology, Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences and Jing'an District Central Hospital of Shanghai, Shanghai Medical College, Fudan University, Shanghai 200030, China.ORCID 0000-0002-1668-0974
Zidan ZhuLaboratory of Tumor Immunology, Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences and Jing'an District Central Hospital of Shanghai, Shanghai Medical College, Fudan University, Shanghai 200030, China.
Lingling GaoDepartment of Anethesiology, Cancer Hospital of Fudan University, Shanghai 200030, China.
Jie QinLaboratory of Tumor Immunology, Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences and Jing'an District Central Hospital of Shanghai, Shanghai Medical College, Fudan University, Shanghai 200030, China.
Binbin LiuLiver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200030, China.
Chunmin LiangLaboratory of Tumor Immunology, Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences and Jing'an District Central Hospital of Shanghai, Shanghai Medical College, Fudan University, Shanghai 200030, China.
Shanghai Medical College of Fudan University · CNMinistry of Education of the People's Republic of China · CNFudan University Shanghai Cancer Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSleep-wake disturbance is prevalent in patients with liver cancer, but there is no direct evidence of its association and related biological mechanisms. Our study was to assess quality of sleep and to describe prevalence of sleep disturbances in patients with different etiologies of liver cancer, especially to explore whether sleep quality influences immune factors.

methodsA total of 210 patients with liver cancer from August 2015 to December 2015 were randomly divided into two groups including HBV cirrhosis and non-HBV cirrhosis. The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate their sleep quality, and then 202 patients enrolled in this study were divided into two groups according to their PSQI scores: PSQI ≤ 5 and PSQI > 5. The association between sleep disturbances and immune factors was analyzed by logistic regression models.

resultsA total of 56.9% of liver cancer patients experienced poor sleep quality (PSQI > 5). The prevalence of sleep disturbances was significantly higher in patients with liver cancer of non-hepatitis B virus (HBV) cirrhosis than with that evolving from HBV cirrhosis (66.7% vs. 50%,

conclusionsMost liver cancer patients suffer from sleep disturbances, especially evolving from non-HBV cirrhosis. A rise in CD3

Indexed as

Liver NeoplasmsSleep Wake DisordersHumansImmunologic FactorsLiver CirrhosisSleepImmunologic FactorsCD3+ T cellsliver cancerNK cellsPSQIsleep disturbances

Identifiers

PMID36290905
PMCPMC9600048
OpenAlexW4306929859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.