Evidence map›Paper›PMID 36290877›Full record

ArticleCurrent oncology (Toronto, Ont.)2022

Predictors of Functional Recovery among Musculoskeletal Oncology Patients Undergoing Lower Extremity Endoprosthetic Reconstruction.

Aaron M Gazendam, Patricia Schneider, Diane Heels-Ansdell, Mohit Bhandari, Jason W Busse, Michelle Ghert

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. The functional recovery trajectory in patients undergoing lower limb salvage surgery for bone tumour: an observational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aaron M GazendamDivision of Orthopaedic Surgery, McMaster University, Hamilton, ON L8S 4L8, Canada.ORCID 0000-0002-2615-4919
Patricia SchneiderDivision of Orthopaedic Surgery, McMaster University, Hamilton, ON L8S 4L8, Canada.
Diane Heels-AnsdellDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON L8S 4L8, Canada.
Mohit BhandariDivision of Orthopaedic Surgery, McMaster University, Hamilton, ON L8S 4L8, Canada.
Jason W BusseDepartment of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON L8S 4L8, Canada.ORCID 0000-0002-0178-8712
Michelle GhertDivision of Orthopaedic Surgery, McMaster University, Hamilton, ON L8S 4L8, Canada.ORCID 0000-0002-4778-4522
Impact · CAMcMaster University · CA

Funding

CIHR 137104
6 · The paper itself

Abstract

BACKGROUND AND

objectivesFunctional outcomes are important for oncology patients undergoing lower extremity reconstruction. The objective of the current study was to describe patient reported function after surgery and identify predictors of postoperative function in musculoskeletal oncology patients undergoing lower extremity endoprosthetic reconstruction.

methodsWe performed a cohort study with functional outcome data from the recently completed

resultsThe 555 patients included in our cohort showed important functional improvement from pre-surgery to 1 year post-surgery (mean difference 14.9 points, 95%CI 12.2 to 17.6;

conclusionsThe majority of patients with tumors of the lower extremity undergoing endoprosthetic reconstruction achieved excellent function at 1 year after surgery. Older age, poor pre-operative function, and endoprosthetic reconstruction for soft tissue sarcomas were associated with worse outcomes; reconstruction for giant cell tumors was associated with better post-operative function. LEVEL OF EVIDENCE: Therapeutic Level IV.

Indexed as

Giant Cell TumorsSarcomaSoft Tissue NeoplasmsAnti-Bacterial AgentsCohort StudiesHumansLimb SalvageLower ExtremityTreatment OutcomeAnti-Bacterial Agentsfunctional outcomesorthopaedic oncologysarcomaToronto extremity salvage score

Identifiers

PMID36290877
PMCPMC9600480
OpenAlexW4306149503

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.