Evidence map›Paper›PMID 36290829›Full record

ReviewCurrent oncology (Toronto, Ont.)2022

Dose-Volume Constraints fOr oRganS At risk In Radiotherapy (CORSAIR): An "All-in-One" Multicenter-Multidisciplinary Practical Summary.

Silvia Bisello, Savino Cilla, Anna Benini, Raffaele Cardano, Nam P Nguyen, Francesco Deodato, Gabriella Macchia, Milly Buwenge, Silvia Cammelli, Tigeneh Wondemagegnehu and 5 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07710040 (Proton PREoperative STereotactic Irradiaiton for High-grade Gliomas), which is not on this map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07710040 phase1recruitingnot on this mapstarted 2026, after this paper: background citation

Proton PREoperative STereotactic Irradiaiton for High-grade Gliomas (PPrestige): a Single-center Prospective Interventional Pahse 1 Trial

TypeinterventionalSponsorNational Medical Research Radiological Centre of the Ministry of Health of RussiaRan2026 to 2029Enrolled9ConditionsHigh Grade GliomasArmsPreoperative irradiation
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  11. Estimation of the α/β ratio for metastatic melanomas in a patient based on actual responses to radiation therapy delivered with various fractionation schedules.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026
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  14. Radiation-induced brachial plexopathy in a patient withReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Silvia BiselloDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum University of Bologna, 40128 Bologna, Italy.ORCID 0000-0003-2358-2499
Savino CillaMedical Physics Unit, Gemelli Molise Hospital-Università Cattolica del Sacro Cuore, 86100 Campobasso, Italy.
Anna BeniniDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum University of Bologna, 40128 Bologna, Italy.
Raffaele CardanoDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum University of Bologna, 40128 Bologna, Italy.
Nam P NguyenDepartment of Radiation Oncology, Howard University College of Medicine, Washington, DC 20059, USA.
Francesco DeodatoRadiation Oncology Unit, Gemelli Molise Hospital-Università Cattolica del Sacro Cuore, 86100 Campobasso, Italy.ORCID 0000-0003-1276-5070
Gabriella MacchiaRadiation Oncology Unit, Gemelli Molise Hospital-Università Cattolica del Sacro Cuore, 86100 Campobasso, Italy.ORCID 0000-0002-0529-201X
Milly BuwengeDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum University of Bologna, 40128 Bologna, Italy.
Silvia CammelliDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum University of Bologna, 40128 Bologna, Italy.ORCID 0000-0003-2111-0164
Tigeneh WondemagegnehuDepartment of Radiation Oncology, Addis Ababa University, Addis Ababa 1000, Ethiopia.
A F M Kamal UddinDepartment of Radiation Oncology, United Hospital Limited, Dhaka 1205, Bangladesh.
Stefania RizzoService of Radiology, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale (EOC), 6500 Lugano, Switzerland.ORCID 0000-0002-5151-0866
Alberto BazzocchiDiagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Lidia StrigariDepartment of Medical Physics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40128 Bologna, Italy.ORCID 0000-0003-4293-2298
Alessio G MorgantiDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum University of Bologna, 40128 Bologna, Italy.ORCID 0000-0001-9793-3410

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe safe use of radiotherapy (RT) requires compliance with dose/volume constraints (DVCs) for organs at risk (OaRs). However, the available recommendations are sometimes conflicting and scattered across a number of different documents. Therefore, the aim of this work is to provide, in a single document, practical indications on DVCs for OaRs in external beam RT available in the literature. MATERIAL AND

methodsA multidisciplinary team collected bibliographic information on the anatomical definition of OaRs, on the imaging methods needed for their definition, and on DVCs in general and in specific settings (curative RT of Hodgkin's lymphomas, postoperative RT of breast tumors, curative RT of pediatric cancers, stereotactic ablative RT of ventricular arrythmia). The information provided in terms of DVCs was graded based on levels of evidence.

resultsOver 650 papers/documents/websites were examined. The search results, together with the levels of evidence, are presented in tabular form.

conclusionsA working tool, based on collected guidelines on DVCs in different settings, is provided to help in daily clinical practice of RT departments. This could be a first step for further optimizations.

Indexed as

RadiosurgeryRadiotherapy, Intensity-ModulatedChildHumansMulticenter Studies as TopicOrgans at RiskRadiotherapy DosageRadiotherapy Planning, Computer-Assisteddose–volume constraintsguidelineliterature revieworgans at riskradiotherapy

Identifiers

PMID36290829
PMCPMC9600677

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.