Evidence map›Paper›PMID 36290781›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Lyso-DGTS Lipid Derivatives Enhance PON1 Activities and Prevent Oxidation of LDL: A Structure-Activity Relationship Study.

Ali Khattib, Sanaa Musa, Majdi Halabi, Tony Hayek, Soliman Khatib

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Effects of Cytokines (or Activating Factors) on Arterial Endothelial Cells.International journal of molecular sciences · 2025
    Review
  3. Review
  4. Article
  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ali KhattibNatural Compounds and Analytical Chemistry Laboratory, MIGAL-Galilee Research Institute, P.O. Box 831, Kiryat Shemona 11016, Israel.ORCID 0000-0001-9574-8684
Sanaa MusaNatural Compounds and Analytical Chemistry Laboratory, MIGAL-Galilee Research Institute, P.O. Box 831, Kiryat Shemona 11016, Israel.ORCID 0000-0002-0014-9038
Majdi HalabiZiv Medical Center, Safed 13100, Israel.
Tony HayekThe Rappaport Family Institute for Research in the Medical Sciences, Rambam Medical Center, Haifa 31096, Israel.
Soliman KhatibNatural Compounds and Analytical Chemistry Laboratory, MIGAL-Galilee Research Institute, P.O. Box 831, Kiryat Shemona 11016, Israel.ORCID 0000-0002-6762-2408
Migal - Galilee Technology Center · ILRappaport Family Institute for Research in the Medical Sciences · ILRebecca Sieff Hospital · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paraoxonase 1 (PON1) plays a role in regulating reverse cholesterol transport and has antioxidative, anti-inflammatory, antiapoptotic, vasodilative, and antithrombotic activities. Scientists are currently focused on the modulation of PON1 expression using different pharmacological, nutritional, and lifestyle approaches. We previously isolated a novel active compound from

Indexed as

antioxidant activitiesdockingLDL oxidationlyso-DGTSparaoxonase 1structure-activity relationship

Identifiers

PMID36290781
PMCPMC9598486
OpenAlexW4306836415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.