Evidence map›Paper›PMID 36290658›Full record

ArticleAntioxidants (Basel, Switzerland)2022

In Vitro Anticancer Activity of Mucoadhesive Oral Films Loaded with

Violeta Popovici, Elena Matei, Georgeta Camelia Cozaru, Laura Bucur, Cerasela Elena Gîrd, Verginica Schröder, Emma Adriana Ozon, Adina Magdalena Musuc, Mirela Adriana Mitu, Irina Atkinson and 8 more

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Bridging bioactive metabolites ofFrontiers in pharmacology · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Autophagy in oral cancer: Promises and challenges (Review).International journal of molecular medicine · 2024
    Review
  11. Review
  12. Article
  13. Implications of the Cultivation of Rosemary and Thyme (International journal of molecular sciences · 2023
    Article
  14. Article
  15. Article
  16. AntibacterialInternational journal of molecular sciences · 2023
    Article
  17. Review
  18. ROS-Induced DNA-Damage and Autophagy in Oral Squamous Cell Carcinoma byInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 3 institutions in 1 country.

Violeta PopoviciDepartment of Microbiology and Immunology, Faculty of Dental Medicine, Ovidius University of Constanta, 900684 Constanta, Romania.ORCID 0000-0001-9696-5728
Elena MateiCenter for Research and Development of the Morphological and Genetic Studies of Malignant Pathology, Ovidius University of Constanta, CEDMOG, 900591 Constanta, Romania.ORCID 0000-0002-8554-7739
Georgeta Camelia CozaruCenter for Research and Development of the Morphological and Genetic Studies of Malignant Pathology, Ovidius University of Constanta, CEDMOG, 900591 Constanta, Romania.
Laura BucurDepartment of Pharmacognosy, Faculty of Pharmacy, Ovidius University of Constanta, 900001 Constanta, Romania.
Cerasela Elena GîrdDepartment of Pharmacognosy, Phytochemistry, and Phytotherapy, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 020956 Bucharest, Romania.ORCID 0000-0003-4372-4335
Verginica SchröderDepartment of Cellular and Molecular Biology, Faculty of Pharmacy, Ovidius University of Constanta, 900001 Constanta, Romania.ORCID 0000-0001-8876-1901
Emma Adriana OzonDepartment of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 020956 Bucharest, Romania.
Adina Magdalena MusucIlie Murgulescu" Institute of Physical Chemistry, Romanian Academy, 060021 Bucharest, Romania.ORCID 0000-0002-6935-8065
Mirela Adriana MituDepartment of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 020956 Bucharest, Romania.ORCID 0000-0002-2831-7574
Irina AtkinsonIlie Murgulescu" Institute of Physical Chemistry, Romanian Academy, 060021 Bucharest, Romania.
Adriana RusuIlie Murgulescu" Institute of Physical Chemistry, Romanian Academy, 060021 Bucharest, Romania.
Simona PetrescuIlie Murgulescu" Institute of Physical Chemistry, Romanian Academy, 060021 Bucharest, Romania.
Raul-Augustin MitranIlie Murgulescu" Institute of Physical Chemistry, Romanian Academy, 060021 Bucharest, Romania.ORCID 0000-0001-6969-2832
Mihai AnastasescuIlie Murgulescu" Institute of Physical Chemistry, Romanian Academy, 060021 Bucharest, Romania.ORCID 0000-0002-4865-2652
Aureliana CaraianeDepartment of Oral Rehabilitation, Faculty of Dental Medicine, Ovidius University of Constanta, 900684 Constanta, Romania.
Dumitru LupuliasaDepartment of Pharmaceutical Technology and Biopharmacy, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 020956 Bucharest, Romania.
Mariana AschieCenter for Research and Development of the Morphological and Genetic Studies of Malignant Pathology, Ovidius University of Constanta, CEDMOG, 900591 Constanta, Romania.
Victoria BadeaDepartment of Microbiology and Immunology, Faculty of Dental Medicine, Ovidius University of Constanta, 900684 Constanta, Romania.
Ovidius University · RORomanian Academy · ROCarol Davila University of Medicine and Pharmacy · RO

Funding

The APC was funded by "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania. This research was supported by the project ANTREPRENORDOC, in the framework of Human Resources Development Operational Programme 2014-2020, financed from the Eur contract number 36355/23.05.2019 HRD OP/380/6/13-SMIS Code: 123847.
6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) is the most frequent oral malignancy, with a high death rate and an inadequate response to conventional chemotherapeutic drugs. Medical research explores plant extracts' properties to obtain potential nanomaterial-based anticancer drugs. The present study aims to formulate, develop, and characterize mucoadhesive oral films loaded with

Indexed as

anticancer potentialantimicrobial activityblood cell culturesCLS-354 cell linemucoadhesive oral filmsoral squamous cell carcinomaoxidative stressUsnea barbata (L.) F. H. Wigg dry acetone extractusnic acid

Identifiers

PMID36290658
PMCPMC9598167
OpenAlexW4297464414

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.