Evidence map›Paper›PMID 36290638›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Inhibitory Effect on Nitric Oxide Release in LPS-Stimulated Macrophages and Free Radical Scavenging Activity of

Jesús García Díaz, Rosalia González Fernández, Julio César Escalona Arranz, Gabriel Llauradó Maury, Daniel Méndez Rodríguez, Linda De Vooght, Enrique Molina, Emmy Tuenter, Luc Pieters, Paul Cos

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Bioactive Extracts and Constituents fromAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Salvimulticanol from3 Biotech · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jesús García DíazPharmacy Department, Faculty of Natural and Exact Sciences, Universidad de Oriente, Santiago de Cuba 90500, Cuba.ORCID 0000-0003-2309-3417
Rosalia González FernándezToxicology and Biomedicine Centre (TOXIMED), Universidad de Ciencias Médicas, Autopista Nacional Km 1½ s/n, Santiago de Cuba 90400, Cuba.
Julio César Escalona ArranzPharmacy Department, Faculty of Natural and Exact Sciences, Universidad de Oriente, Santiago de Cuba 90500, Cuba.ORCID 0000-0003-3609-4451
Gabriel Llauradó MauryCenter of Studies for Industrial Biotechnology (CEBI), Universidad de Oriente, Santiago de Cuba 90500, Cuba.ORCID 0000-0001-5961-9375
Daniel Méndez RodríguezChemistry Department, Faculty of Applied Sciences, Universidad de Camagüey, Carretera de Circunvalación Km 512, Camagüey 74650, Cuba.ORCID 0000-0001-7148-3191
Linda De VooghtLaboratory of Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Enrique MolinaChemistry Department, Faculty of Applied Sciences, Universidad de Camagüey, Carretera de Circunvalación Km 512, Camagüey 74650, Cuba.
Emmy TuenterNatural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0003-3765-0341
Luc PietersNatural Products & Food Research and Analysis (NatuRA), Department of Pharmaceutical Sciences, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0002-8288-4254
Paul CosLaboratory of Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, 2610 Antwerp, Belgium.ORCID 0000-0003-4361-8911

Funding

Vlaamse Interuniversitaire Raad CU2017TEA433A102Vlaamse Interuniversitaire Raad CU2019IUC030A105-77143
6 · The paper itself

Abstract

Oxidative stress is an important component of many diseases including cancer, along with inflammatory and neurodegenerative processes. Natural antioxidants have emerged as promising substances to protect the human body against reactive oxygen and nitrogen species. The present study evaluates the inhibition of nitric oxide (NO) production in LPS-stimulated RAW 264.7 murine macrophages and the free radical scavenging activity of

Indexed as

alkaloidsantioxidantsCroton linearisflavonoidsnitric oxide release

Identifiers

PMID36290638
PMCPMC9598791

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.