Evidence map›Paper›PMID 36290620›Full record

ArticleAntioxidants (Basel, Switzerland)2022

Dipeptide Repeat Pathology in

José Jiménez-Villegas, Janine Kirby, Ana Mata, Susana Cadenas, Martin R Turner, Andrea Malaspina, Pamela J Shaw, Antonio Cuadrado, Ana I Rojo

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Targeting GeneInternational journal of molecular sciences · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Mitochondrial Dysfunction in Repeat Expansion Diseases.Antioxidants (Basel, Switzerland) · 2023
    Review
  9. Bilirubin and Redox Stress in Age-Related Brain Diseases.Antioxidants (Basel, Switzerland) · 2023
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

José Jiménez-VillegasDepartment of Biochemistry, Medical College, Autonomous University of Madrid (UAM), 28029 Madrid, Spain.ORCID 0000-0003-3967-1832
Janine KirbySheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK.ORCID 0000-0002-7468-5917
Ana MataCentro de Biología Molecular "Severo Ochoa" (CSIC/UAM), 28049 Madrid, Spain.ORCID 0000-0002-1582-8316
Susana CadenasCentro de Biología Molecular "Severo Ochoa" (CSIC/UAM), 28049 Madrid, Spain.
Martin R TurnerNuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DU, UK.
Andrea MalaspinaNeuroscience and Trauma Centre, Blizard Institute, Barts and The London School of Medicine & Dentistry, Queen Mary University of London, London E1 2AT, UK.
Pamela J ShawSheffield Institute for Translational Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK.ORCID 0000-0002-8925-2567
Antonio CuadradoDepartment of Biochemistry, Medical College, Autonomous University of Madrid (UAM), 28029 Madrid, Spain.ORCID 0000-0002-4039-7140
Ana I RojoDepartment of Biochemistry, Medical College, Autonomous University of Madrid (UAM), 28029 Madrid, Spain.ORCID 0000-0002-0312-5867
Biomedical Research Networking Center on Neurodegenerative Diseases · ESCentro de Biología Molecular Severo Ochoa · ESUniversity of Sheffield · GBQueen Mary University of London · GBUniversity of Oxford · GB

Funding

Medical Research Council MR/S004920/1Motor Neurone Disease Association AMBRoSIA 972-797 and NECTAR 974-797 awardsMotor Neurone Disease Association MALASPINA/APR13/817-791Motor Neurone Disease Association NECTAR/OCT15/974-797Motor Neurone Disease Association TURNER/OCT15/972-797Motor Neurone Disease Association TURNER/OCT18/989-797
6 · The paper itself

Abstract

The hexanucleotide expansion of the

Indexed as

amyotrophic lateral sclerosisC9orf72dipeptide repeat proteinsNRF2

Identifiers

PMID36290620
PMCPMC9598689
OpenAlexW4297147900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.