ReviewBioengineering (Basel, Switzerland)2022
Plate Augmentation in Aseptic Femoral Shaft Nonunion after Intramedullary Nailing: A Literature Review.
Review in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Effectiveness and safety of augmentative plating technique in managing nonunion following intramedullary nailing of long bones in the lower extremity: A systematic review and meta-analysis.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025Pooled it
- Anticipating femoral shaft nonunion at 1-3 months: a multimodal framework with automated X‑ray segmentation despite metal implants.International orthopaedics · 2026Article
- Fibular Nonunion: A Systematic Review of Incidence, Diagnosis, and Treatment Outcomes.Journal of personalized medicine · 2026Review
- Factors Associated with Bone Union Failure After Frozen Autograft Reconstruction in Lower Limb Osteosarcoma.Cancers · 2025Article
- Development and validation of a nomogram model for predicting postoperative nonunion in femoral shaft fractures.BMC musculoskeletal disorders · 2025Article
- Intramedullary Nailing in Femoral Diaphyseal Fractures: A Retrospective Multicenter Cohort Study.Life (Basel, Switzerland) · 2025Article
- Comparative Study of Exchange Nailing and Augmentative Plating for Treating Aseptic Nonunion of Femoral Shafts Post Intramedullary Nailing: A Single-Blind, Multicentric Randomized Clinical Trial.Journal of clinical medicine · 2024Article
- Comparison of treatment results of femoral shaft fracture with two methods of intramedullary nail (IMN) and plate.BMC surgery · 2024Article
- Nonunion Fractures: Trends in Epidemiology and Treatment of Femur Fractures, 2017-2022.Cureus · 2024Article
- Management of infected bone defects of the femoral shaft by Masquelet technique: sequential internal fixation and nail with plate augmentation.BMC musculoskeletal disorders · 2024Article
- Delayed Union and Nonunion: Current Concepts, Prevention, and Correction: A Review.Bioengineering (Basel, Switzerland) · 2024Review
- Icariin-Enhanced Osteoclast-Derived Exosomes Promote Repair of Infected Bone Defects by Regulating Osteoclast and Osteoblast Communication.International journal of nanomedicine · 2024Article
- Induced membrane technique versus one-stage autografting in management of atrophic nonunion of long bone in the lower limb: clinical and health burden outcomes.Journal of orthopaedic surgery and research · 2023Article
- Sildenafil, a phosphodiesterase-5 inhibitor, stimulates angiogenesis and bone regeneration in an atrophic non-union model in mice.Journal of translational medicine · 2023Article
- Fixators dynamization for delayed union and non-union of femur and tibial fractures: a review of techniques, timing and influence factors.Journal of orthopaedic surgery and research · 2023Review
- Augmentative Plating versus Exchange Intramedullary Nailing for the Treatment of Aseptic Non-Unions of the Femoral Shaft-A Biomechanical Study in a SawboneJournal of personalized medicine · 2023Article
- Use of Teriparatide in preventing delayed bone healing and nonunion: a multicentric study on a series of 20 patients.BMC musculoskeletal disorders · 2023Article
- Trochanteric and subtrochanteric fractures irreducible by closed reduction: a retrospective study.Journal of orthopaedic surgery and research · 2023Article
- Minimally Invasive Derotational Osteotomy of Long Bones: Smartphone Application Used to Improve the Accuracy of Correction.Journal of clinical medicine · 2023Article
- Intramedullary nailing as a treatment for non-unions of femoral shaft fractures after plating failure: A case series.International journal of surgery case reports · 2023Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFemoral shaft fractures (FSFs) are a frequent injury in traumatology for which intramedullary nailing (IMN) is considered the gold standard treatment. Nonunion (NU) is one of the most frequent complications in FSF treated with IMN, with a percentage from 1.1% to 14%. Plate augmentation (PA), the addition of a compression plate and screws, with or without bone graft has been described as an effective option for the treatment of NU, improving the biomechanical conditions at the fracture site. The aim of this review was to analyze the literature relating to the use of PA in NU after IMN in FSFs to assess the efficacy of the technique.
methodsAn electronic search on PubMed, Google Scholar, and Web of Science was conducted to search for all studies concerning PA of femoral shaft NUs after IMN.
resultsTwenty-four studies were included in the review comprising a total of 502 patients with a mean age of 39.5 years. Of these, 200 hundred patients had atrophic pseudoarthrosis and 123 had hypertrophic pseudoarthrosis, while in 179, the type of pseudoarthrosis was not reported. The most frequently used plate for PA was the dynamic compression plate (DCP); in 87.1% of the cases, the authors added a bone graft to the plate fixation. In 98.0% of the patients, a complete bone union was achieved in a mean time of 5.8 ± 2.12 months.
conclusionThe patients treated with PA included in this review showed a good rate of consolidation in the femoral shaft NUs, with good functional recovery and a low incidence of complications.
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Registered trials
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