Evidence map›Paper›PMID 36290495›Full record

ArticleBioengineering (Basel, Switzerland)2022

Layer-Specific Damage Modeling of Porcine Large Intestine under Biaxial Tension.

Aroj Bhattarai, Charlotte Anabell May, Manfred Staat, Wojciech Kowalczyk, Thanh Ngoc Tran

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Aroj BhattaraiDepartment of Orthopaedic Surgery, University of Saarland, 66424 Homburg, Germany.ORCID 0000-0003-2223-2200
Charlotte Anabell MayInstitute of Bioengineering, FH Aachen University of Applied Sciences, 52428 Jülich, Germany.
Manfred StaatInstitute of Bioengineering, FH Aachen University of Applied Sciences, 52428 Jülich, Germany.ORCID 0000-0003-4363-6570
Wojciech KowalczykChair of Mechanics and Robotics, University of Duisburg-Essen, 47057 Duisburg, Germany.ORCID 0000-0002-7390-2836
Thanh Ngoc TranDepartment of Orthopaedic Surgery, University of Saarland, 66424 Homburg, Germany.ORCID 0000-0001-8997-3201
FH Aachen · DESaarland University · DEUniversity of Duisburg-Essen · DE

Funding

Deutsche Forschungsgemeinschaft TR 1487/2-1 and KO 3396/16-1
6 · The paper itself

Abstract

The mechanical behavior of the large intestine beyond the ultimate stress has never been investigated. Stretching beyond the ultimate stress may drastically impair the tissue microstructure, which consequently weakens its healthy state functions of absorption, temporary storage, and transportation for defecation. Due to closely similar microstructure and function with humans, biaxial tensile experiments on the porcine large intestine have been performed in this study. In this paper, we report hyperelastic characterization of the large intestine based on experiments in 102 specimens. We also report the theoretical analysis of the experimental results, including an exponential damage evolution function. The fracture energies and the threshold stresses are set as damage material parameters for the longitudinal muscular, the circumferential muscular and the submucosal collagenous layers. A biaxial tensile simulation of a linear brick element has been performed to validate the applicability of the estimated material parameters. The model successfully simulates the biomechanical response of the large intestine under physiological and non-physiological loads.

Indexed as

anisotropybiaxial tensile experimentconstitutive modelingdamagehyperelastic

Identifiers

PMID36290495
PMCPMC9598910
OpenAlexW4303613951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.