Evidence map›Paper›PMID 36290322›Full record

ArticleBiology2022

Polymorphisms in

Isabel de Rojas, César Martin-Montero, Maria Fedetz, Adela González-Jiménez, Fuencisla Matesanz, Elena Urcelay, Laura Espino-Paisán

Open access · goldAbstract read
In one paragraph

Article in Biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Isabel de RojasGenetics and Molecular Bases of Complex Diseases Laboratory, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
César Martin-MonteroGenetics and Molecular Bases of Complex Diseases Laboratory, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Maria FedetzDepartment of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina "López Neyra", Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), 18016 Granada, Spain.
Adela González-JiménezGenetics and Molecular Bases of Complex Diseases Laboratory, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Fuencisla MatesanzDepartment of Cell Biology and Immunology, Instituto de Parasitología y Biomedicina "López Neyra", Consejo Superior de Investigaciones Científicas (IPBLN-CSIC), 18016 Granada, Spain.ORCID 0000-0002-9429-1819
Elena UrcelayGenetics and Molecular Bases of Complex Diseases Laboratory, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.ORCID 0000-0001-8470-8396
Laura Espino-PaisánGenetics and Molecular Bases of Complex Diseases Laboratory, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), 28040 Madrid, Spain.
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos · ESConsejo Superior de Investigaciones Científicas · ES

Funding

Agencia estatal de investigación PROYECTO/AEI/10.13039/50110001103Instituto de Salud Carlos III PI16/01259Instituto de Salud Carlos III PI20/01634Ministerio de Ciencia e Innovación FPU20/03387
6 · The paper itself

Abstract

Disrupted circadian cycle has been reported in multiple sclerosis (MS). Previous genome-wide association studies (GWAS) singled out over 230 variants associated with MS. A study performed in a Slavic population identified two new single nucleotide polymorphisms (SNPs), rs6811520 (

Indexed as

autoimmune diseasecircadian rhythmgenetic associationmultiple sclerosis

Identifiers

PMID36290322
PMCPMC9598657
OpenAlexW4297464433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.