Evidence map›Paper›PMID 36289967›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Potentiation of Antibiotic Action and Efflux Pump Inhibitory Effect on

Ana Raquel Pereira da Silva, Maria do Socorro Costa, Nara Juliana Santos Araújo, Thiago Sampaio de Freitas, Ray Silva de Almeida, José Maria Barbosa Filho, Josean Fechine Tavares, Erlânio Oliveira de Souza, Pablo Antonio Maia de Farias, Jacqueline Cosmo Andrade Pinheiro and 1 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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  3. Article
  4. Review
  5. Endophytic Fungus UJ3-2 fromMolecules (Basel, Switzerland) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Ana Raquel Pereira da SilvaGraduate Program in Biotechnology, Universidade Estadual do Ceará-UECE, Fortaleza 60714-903, Brazil.
Maria do Socorro CostaGraduate Program in Biotechnology, Universidade Estadual do Ceará-UECE, Fortaleza 60714-903, Brazil.ORCID 0000-0002-7138-6348
Nara Juliana Santos AraújoGraduate Program in Health Sciences, Universidade Federal do Cariri-UFCA, Barbalha 63180-000, Brazil.
Thiago Sampaio de FreitasDepartment of Biological Chemistry, Universidade Regional do Cariri-URCA, Crato 63105-000, Brazil.
Ray Silva de AlmeidaDepartment of Biological Chemistry, Universidade Regional do Cariri-URCA, Crato 63105-000, Brazil.ORCID 0000-0001-7463-5648
José Maria Barbosa FilhoLaboratory of Pharmaceutical Technology, Universidade Federal da Paraíba-UFPB, João Pessoa 58033-455, Brazil.ORCID 0000-0002-9567-4096
Josean Fechine TavaresDepartment of Pharmaceutical Sciences, Universidade Federal da Paraíba-UFPB, João Pessoa 58051-900, Brazil.ORCID 0000-0003-0293-2605
Erlânio Oliveira de SouzaFaculty of Technology of Cariri, Juazeiro do Norte 63040-000, Brazil.
Pablo Antonio Maia de FariasCollege of Dentistry-CECAPE, Juazeiro do Norte 63024-015, Brazil.ORCID 0000-0002-0179-2164
Jacqueline Cosmo Andrade PinheiroGraduate Program in Health Sciences, Universidade Federal do Cariri-UFCA, Barbalha 63180-000, Brazil.
Henrique Douglas Melo CoutinhoDepartment of Biological Chemistry, Universidade Regional do Cariri-URCA, Crato 63105-000, Brazil.ORCID 0000-0002-6634-4207
Universidade Federal do Cariri · BRUniversidade Regional do Cariri · BRUniversidade Estadual do Ceará · BRUniversidade Federal da Paraíba · BRFucape Business School · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A worrisome fact is the increase in microbial resistance, which has as its main cause the indiscriminate use of antibiotics. Scientific studies have investigated bioactive compounds such as steroidal sapogenins, in the perspective of new beneficial alternatives for the control of bacterial resistance. Therefore, the objective of this work was to verify the antibacterial activity as well as the modifying action of antibiotics associated with solasodine and its ability to inhibit the efflux pump mechanism in strains of

Indexed as

antibacterial activitybacterial resistancesapogenin

Identifiers

PMID36289967
PMCPMC9598803
OpenAlexW4297347656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.