Evidence map›Paper›PMID 36289958›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Determination of the Elution Capacity of Dalbavancin in Bone Cements: New Alternative for the Treatment of Biofilm-Related Peri-Prosthetic Joint Infections Based on an

Mar Sánchez-Somolinos, Marta Díaz-Navarro, Antonio Benjumea, Marta Tormo, José Matas, Javier Vaquero, Patricia Muñoz, Pablo Sanz-Ruíz, María Guembe

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Antimicrobial 3D printed implants for periprosthetic joint infections.Drug delivery and translational research · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mar Sánchez-SomolinosDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Marta Díaz-NavarroDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0002-1572-8040
Antonio BenjumeaDepartment of Orthopaedic Surgery and Traumatology, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Marta TormoSchool of Biology, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0001-9572-6194
José MatasDepartment of Orthopaedic Surgery and Traumatology, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.
Javier VaqueroInstituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0002-8785-2278
Patricia MuñozInstituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0001-5706-5583
Pablo Sanz-RuízInstituto de Investigación Sanitaria Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0002-7588-1880
María GuembeDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain.ORCID 0000-0002-7607-5848
Hospital General Universitario Gregorio Marañón · ESUniversidad Complutense de Madrid · ES

Funding

Consejería de Educación, Juventud y Deporte PEJD-2020-AI_BMD-17971Fundación Mutua Madrileña FMM21/01Instituto de Salud Carlos III MSII/00008Instituto de Salud Carlos III PI21/00344
6 · The paper itself

Abstract

Antibiotic-loaded bone cement is the most widely used approach for the treatment of biofilm-induced septic sequelae in orthopedic surgery. Dalbavancin is a lipoglycopeptide that acts against Gram-positive bacteria and has a long half-life, so we aimed to assess whether it could be a new alternative drug in antibiotic-loaded bone cement for the treatment of periprosthetic joint infections. We assessed the elution capacity of dalbavancin and compared it with that of vancomycin in bone cement. Palacos

Indexed as

bone cementcumulative concentrationdalbavancinelutionpolymethylmethacrylatevancomycin

Identifiers

PMID36289958
PMCPMC9598415
OpenAlexW4297149762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.