Evidence map›Paper›PMID 36289893›Full record

ArticleBiomedicines2022

Transcranial Magnetic Stimulation Following a Paired Associative Stimulation Protocol Based on a Video Game Neuromodulates Cortical Excitability and Motor Behavior.

Arantzazu San Agustín, Guillermo Asín-Prieto, Juan C Moreno, Antonio Oliviero, José L Pons

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Arantzazu San AgustínNeural Rehabilitation Group (NRG), Cajal Institute, Consejo Superior de Investigaciones Científicas (CSIC), 28002 Madrid, Spain.ORCID 0000-0003-1417-5461
Guillermo Asín-PrietoNeural Rehabilitation Group (NRG), Cajal Institute, Consejo Superior de Investigaciones Científicas (CSIC), 28002 Madrid, Spain.ORCID 0000-0003-0688-7944
Juan C MorenoNeural Rehabilitation Group (NRG), Cajal Institute, Consejo Superior de Investigaciones Científicas (CSIC), 28002 Madrid, Spain.ORCID 0000-0001-9561-7764
Antonio OlivieroFENNSI Group, Hospital Nacional de Parapléjicos, SESCAM, 45004 Toledo, Spain.
José L PonsNeural Rehabilitation Group (NRG), Cajal Institute, Consejo Superior de Investigaciones Científicas (CSIC), 28002 Madrid, Spain.
Consejo Superior de Investigaciones Científicas · ESNorthwestern University · USHospital San Pedro · ES

Funding

Consejo Superior de Investigaciones Científicas Intramural project 201850E062European social fund through the Youth Employment Operational Program and the Youth Em-ployment Initiative of the Comunidad de Madrid Within the framework of order 2811/2016
6 · The paper itself

Abstract

Transcranial Magnetic Stimulation (TMS) can be used to modulate cortico-spinal excitability following a paired associative stimulation (PAS) protocol. Movement-related cortical stimulation (MRCS) is a PAS protocol based on the synchronization of a single-pulse TMS with a movement task. However, plasticity and motor performance potentiation due to MRCS has been related exclusively to single-movement tasks. In order to unveil the effects of an MRCS protocol in complex movements, we applied PAS synchronized with a movement-related dynamic task (MRDT) with a customized video game. In 22 healthy subjects, we measured the reaction time (RT), trajectory error (TE), and the number of collected and avoided items when playing the custom video game to evaluate the task motor performance. Moreover, we assessed the recruitment curve of Motor Evoked Potentials (MEPs) with five different intensities to evaluate the motor corticospinal excitability. MEPs were recorded in

Indexed as

corticospinal plasticityfatiguemovement-related cortical stimulationpaired associative stimulationreaction timeTranscranial Magnetic Stimulationvideo game

Identifiers

PMID36289893
PMCPMC9599957
OpenAlexW4306839109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.