Evidence map›Paper›PMID 36289862›Full record

ReviewBiomedicines2022

The Arrival of the Metaverse in Neurorehabilitation: Fact, Fake or Vision?

Rocco Salvatore Calabrò, Antonio Cerasa, Irene Ciancarelli, Loris Pignolo, Paolo Tonin, Marco Iosa, Giovanni Morone

Abstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Metaverse-Related and Immersive Digital Technologies in Neurorehabilitation: A Scoping Review.Archives of rehabilitation research and clinical translation · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. The application of metaverse in mental health.Frontiers in public health · 2025
    Review
  10. Journal of medical extended reality · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rocco Salvatore CalabròIRCCS Centro Neurolesi "Bonino-Pulejo", 98123 Messina, Italy.
Antonio CerasaInstitute for Biomedical Research and Innovation (IRIB), National Research Council of Italy, 98164 Messina, Italy.ORCID 0000-0002-8022-4770
Irene CiancarelliDepartment of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0001-6666-0245
Loris PignoloS. Anna Institute, 1680067 Crotone, Italy.ORCID 0000-0001-9706-0779
Paolo ToninS. Anna Institute, 1680067 Crotone, Italy.ORCID 0000-0002-4867-1378
Marco IosaDepartment of Psychology, Sapienza University of Rome, 00185 Rome, Italy.
Giovanni MoroneDepartment of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The metaverse is a new technology thought to provide a deeper, persistent, immersive 3D experience combining multiple different virtual approaches in a full continuum of physical-digital interaction spaces. Different from virtual reality (VR) and augmented reality (AR), the metaverse has a service-oriented solid model with an emphasis on social and content dimensions. It has widely been demonstrated that motor or cognitive deficits can be more effectively treated using VR/AR tools, but there are several issues that limit the real potential of immersive technologies applied to neurological patients. In this scoping review, we propose future research directions for applying technologies extracted from the metaverse in clinical neurorehabilitation. The multisensorial properties of the metaverse will boost the embodied cognition experience, thus influencing the internal body representations as well as learning strategies. Moreover, the immersive social environment shared with other patients will contribute to recovering social and psychoemotional abilities. In addition to the many potential pros, we will also discuss the cons, providing readers with the available information to better understand the complexity and limitations of the metaverse, which could be considered the future of neurorehabilitation.

Indexed as

artificial intelligencebody schema representationcognitive impairmentmetaversemovement disordersmultisensory feedbackneurorehabilitationvirtual reality

Identifiers

PMID36289862
PMCPMC9599848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.