Evidence map›Paper›PMID 36289838›Full record

ReviewBiomedicines2022

Radiologist versus Non-Radiologist Detection of Lymph Node Metastasis in Papillary Thyroid Carcinoma by Ultrasound: A Meta-Analysis.

Peter P Issa, Lauren Mueller, Mohammad Hussein, Aaron Albuck, Mohamed Shama, Eman Toraih, Emad Kandil

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Peter P IssaSchool of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.ORCID 0000-0002-5248-3142
Lauren MuellerSchool of Medicine, Tulane University, New Orleans, LA 70112, USA.ORCID 0000-0002-6459-9839
Mohammad HusseinDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Aaron AlbuckSchool of Medicine, Tulane University, New Orleans, LA 70112, USA.
Mohamed ShamaDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Eman ToraihDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.ORCID 0000-0001-9267-3787
Emad KandilDepartment of Surgery, School of Medicine, Tulane University, New Orleans, LA 70112, USA.
Tulane University · USLouisiana State University Health Sciences Center New Orleans · USSuez Canal University · EG

Funding

American Thyroid Association THYROIDGRANT2021-0000000232Tulane University Bridge Fund
6 · The paper itself

Abstract

Papillary thyroid carcinoma (PTC) is the most common thyroid cancer worldwide and is known to spread to adjacent neck lymphatics. Lymph node metastasis (LNM) is a known predictor of disease recurrence and is an indicator for aggressive resection. Our study aims to determine if ultrasound sonographers' degree of training influences overall LNM detection. PubMed, Embase, and Scopus articles were searched and screened for relevant articles. Two investigators independently screened and extracted the data. Diagnostic test parameters were determined for all studies, studies reported by radiologists, and studies reported by non-radiologists. The total sample size amounted to 5768 patients and 10,030 lymph nodes. Radiologists performed ultrasounds in 18 studies, while non-radiologists performed ultrasounds in seven studies, corresponding to 4442 and 1326 patients, respectively. The overall sensitivity of LNM detection by US was 59% (95%CI = 58-60%), and the overall specificity was 85% (95%CI = 84-86%). The sensitivity and specificity of US performed by radiologists were 58% and 86%, respectively. The sensitivity and specificity of US performed by non-radiologists were 62% and 78%, respectively. Summary receiver operating curve (sROC) found radiologists and non-radiologists to detect LNM on US with similar accuracy (

Indexed as

lymph node metastasisradiologistthyroid cancerultrasound

Identifiers

PMID36289838
PMCPMC9599420
OpenAlexW4306362177

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.