Evidence map›Paper›PMID 36289705›Full record

ArticleBiomedicines2022

FYCO1 Increase and Effect of Arimoclomol-Treatment in Human

Anne-Katrin Guettsches, Nancy Meyer, René P Zahedi, Teresinha Evangelista, Thomas Muentefering, Tobias Ruck, Emmanuelle Lacene, Christoph Heute, Humberto Gonczarowska-Jorge, Benedikt Schoser and 4 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 3 countries.

Anne-Katrin GuettschesDepartment of Neurology, Heimer Institute for Muscle Research, University Hospital Bergmannsheil, Ruhr University Bochum, 44789 Bochum, Germany.ORCID 0000-0002-4017-940X
Nancy MeyerDepartment of Neuropediatrics and Neuromuscular Centre for Children and Adolescents, Center for Translational Neuro- and Behavioral Sciences, University Duisburg-Essen, 45147 Essen, Germany.
René P ZahediManitoba Centre for Proteomics and Systems Biology, 715 McDermot Aveue, Winnipeg, MB R3E 3P4, Canada.
Teresinha EvangelistaNord/Est/Ile-de-France Neuromuscular Reference Center, Unité de Morphologie Neuromusculaire, Institute of Myology, Pitié-Salpêtrière Hospital, APHP, Sorbonne University, 75013 Paris, France.
Thomas MuenteferingDepartment of Neurology, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.
Tobias RuckDepartment of Neurology, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany.ORCID 0000-0001-6332-8650
Emmanuelle LaceneNord/Est/Ile-de-France Neuromuscular Reference Center, Unité de Morphologie Neuromusculaire, Institute of Myology, Pitié-Salpêtrière Hospital, APHP, Sorbonne University, 75013 Paris, France.
Christoph HeuteDepartment of Neuropediatrics and Neuromuscular Centre for Children and Adolescents, Center for Translational Neuro- and Behavioral Sciences, University Duisburg-Essen, 45147 Essen, Germany.
Humberto Gonczarowska-JorgeLeibniz-Institut für Analytische Wissenschaften-ISAS-e.V, 44227 Dortmund, Germany.
Benedikt SchoserDepartment of Neurology, Friedrich-Baur-Institute, Ludwig-Maximilians-University Munich, Ziemssenstr. 1a, 80336 Munich, Germany.ORCID 0000-0002-2757-8131
Sabine KrauseDepartment of Neurology, Friedrich-Baur-Institute, Ludwig-Maximilians-University Munich, Ziemssenstr. 1a, 80336 Munich, Germany.ORCID 0000-0002-3141-886X
Andreas HentschelLeibniz-Institut für Analytische Wissenschaften-ISAS-e.V, 44227 Dortmund, Germany.ORCID 0000-0002-0272-9220
Matthias VorgerdDepartment of Neurology, Heimer Institute for Muscle Research, University Hospital Bergmannsheil, Ruhr University Bochum, 44789 Bochum, Germany.ORCID 0000-0002-1782-4642
Andreas RoosDepartment of Neurology, Heimer Institute for Muscle Research, University Hospital Bergmannsheil, Ruhr University Bochum, 44789 Bochum, Germany.
BG University Hospital Bergmannsheil Bochum · DEHeinrich Heine University Düsseldorf · DELeibniz Institute for Analytical Sciences - ISAS · DELudwig-Maximilians-Universität München · DESorbonne Université · FRChildren's Hospital of Eastern Ontario · CAResearch Manitoba · CA

Funding

French Muscular Dystrophy Association 21644
6 · The paper itself

Abstract

Dominant

Indexed as

arimoclomolautophagyDDX58fibroblast proteomicsFYCO1GBP1inclusion body myopathy with frontotemporal dementia and Paget’s disease of the bone (IBMPFD)valosin–containing protein (VCP)

Identifiers

PMID36289705
PMCPMC9598455
OpenAlexW4303613937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.