Evidence map›Paper›PMID 36289694›Full record

ArticleBiomedicines2022

Curcumin Hybrid Lipid Polymeric Nanoparticles: Antioxidant Activity, Immune Cellular Response, and Cytotoxicity Evaluation.

María Isabel Quirós-Fallas, Krissia Wilhelm-Romero, Silvia Quesada-Mora, Gabriela Azofeifa-Cordero, Luis Felipe Vargas-Huertas, Diego Alvarado-Corella, Juan José Mora-Román, José Roberto Vega-Baudrit, Mirtha Navarro-Hoyos, Andrea Mariela Araya-Sibaja

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

María Isabel Quirós-FallasLaboratorio BIODESS, Escuela de Química, Universidad de Costa Rica, San Pedro de Montes de Oca, San José 2060, Costa Rica.ORCID 0000-0003-1377-6935
Krissia Wilhelm-RomeroLaboratorio BIODESS, Escuela de Química, Universidad de Costa Rica, San Pedro de Montes de Oca, San José 2060, Costa Rica.ORCID 0000-0003-3763-1626
Silvia Quesada-MoraDepartmento de Bioquímica, Escuela de Medicina, Universidad de Costa Rica, San Pedro de Montes de Oca, San José 2060, Costa Rica.ORCID 0000-0003-1926-5378
Gabriela Azofeifa-CorderoDepartmento de Bioquímica, Escuela de Medicina, Universidad de Costa Rica, San Pedro de Montes de Oca, San José 2060, Costa Rica.ORCID 0000-0002-2484-9207
Luis Felipe Vargas-HuertasLaboratorio BIODESS, Escuela de Química, Universidad de Costa Rica, San Pedro de Montes de Oca, San José 2060, Costa Rica.ORCID 0000-0002-6270-0403
Diego Alvarado-CorellaLaboratorio BIODESS, Escuela de Química, Universidad de Costa Rica, San Pedro de Montes de Oca, San José 2060, Costa Rica.
Juan José Mora-RománFacultad de Farmacia, Universidad de Costa Rica, San Pedro de Montes de Oca, San José 2060, Costa Rica.ORCID 0000-0001-9148-3025
José Roberto Vega-BaudritLaboratorio Nacional de Nanotecnología LANOTEC-CeNAT-CONARE, Pavas, San José 1174-1200, Costa Rica.ORCID 0000-0002-2002-1744
Mirtha Navarro-HoyosLaboratorio BIODESS, Escuela de Química, Universidad de Costa Rica, San Pedro de Montes de Oca, San José 2060, Costa Rica.ORCID 0000-0003-2115-4677
Andrea Mariela Araya-SibajaLaboratorio Nacional de Nanotecnología LANOTEC-CeNAT-CONARE, Pavas, San José 1174-1200, Costa Rica.ORCID 0000-0001-9809-6079
Universidad de Costa Rica · CRUniversidad Nacional · CR

Funding

CONICIT-MICITT FI-0006-20University of Costa Rica 115C0001 & 115C1515
6 · The paper itself

Abstract

Poor solubility and short biological half-life present a challenge that needs to be overcome in order to improve the recognized bioactivities of curcumin (CUR), the main phenolic compounds derived from the roots of

Indexed as

antioxidant activitycurcumincytotoxicityhybrid lipid polymeric nanoparticlesImmune cellular responsenanoparticle characterization

Identifiers

PMID36289694
PMCPMC9599193
OpenAlexW4297973623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.