Evidence map›Paper›PMID 36289679›Full record

ArticleBiomedicines2022

T Lymphocyte Serotonin 5-HT

Flora Reverchon, Colleen Guillard, Lucile Mollet, Pascal Auzou, David Gosset, Fahima Madouri, Antoine Valéry, Arnaud Menuet, Canan Ozsancak, Maud Pallix-Guyot and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Flora ReverchonUMR7355, Experimental and Molecular Immunology and Neurogenetics, CNRS and University of Orléans, 45071 Orleans, France.
Colleen GuillardUPR4301, Center for Molecular Biophysics, CNRS, 45071 Orleans, France.
Lucile MolletUPR4301, Center for Molecular Biophysics, CNRS, 45071 Orleans, France.
Pascal AuzouNeurology Department, Regional Hospital Orleans, 45100 Orleans, France.
David GossetUPR4301, Center for Molecular Biophysics, CNRS, 45071 Orleans, France.ORCID 0000-0003-3143-0815
Fahima MadouriUPR4301, Center for Molecular Biophysics, CNRS, 45071 Orleans, France.
Antoine ValéryMedical Information Department, Regional Hospital Orleans, 45100 Orleans, France.ORCID 0000-0002-7916-7318
Arnaud MenuetUMR7355, Experimental and Molecular Immunology and Neurogenetics, CNRS and University of Orléans, 45071 Orleans, France.
Canan OzsancakNeurology Department, Regional Hospital Orleans, 45100 Orleans, France.ORCID 0000-0002-5537-5630
Maud Pallix-GuyotNeurology Department, Regional Hospital Orleans, 45100 Orleans, France.
Séverine Morisset-LopezUPR4301, Center for Molecular Biophysics, CNRS, 45071 Orleans, France.ORCID 0000-0002-9930-7824
Centre National de la Recherche Scientifique · FRCentre hospitalier universitaire d'Orléans · FRUniversité d'Orléans · FR

Funding

APR IR NeuroMabster
6 · The paper itself

Abstract

Serotonin (5-HT) is known as a potent immune cell modulator in autoimmune diseases and should be protective in the pathogenesis of multiple sclerosis (MS). Nevertheless, there is limited knowledge about receptors involved in 5-HT effects as well as induced mechanisms. Among 5-HT receptors, the 5-HT

Indexed as

5-HT7 receptorinterleukin-10 (IL-10)multiple sclerosisnatalizumab treatmentPBMCs (peripheral blood mononuclear cells)serotoninT lymphocyte (T-cell)

Identifiers

PMID36289679
PMCPMC9599221
OpenAlexW4297348183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.