Evidence map›Paper›PMID 36289623›Full record

ArticleBiomedicines2022

Comparable Outcomes in Early Hepatocellular Carcinomas Treated with Trans-Arterial Chemoembolization and Radiofrequency Ablation.

Benjamin Wei Rong Tay, Daniel Q Huang, Muthiah Mark, Neo Wee Thong, Lee Guan Huei, Lim Seng Gee, Low How Cheng, Lee Yin Mei, Prem Thurairajah, Lim Jia Chen and 8 more

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

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  7. [Guidelines for image-guided ablation of primary liver cancer (2023 version)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Benjamin Wei Rong TayDivision of Gastroenterology and Hepatology, National University Health System, Singapore 119228, Singapore.ORCID 0000-0002-9000-2936
Daniel Q HuangDivision of Gastroenterology and Hepatology, National University Health System, Singapore 119228, Singapore.
Muthiah MarkDivision of Gastroenterology and Hepatology, National University Health System, Singapore 119228, Singapore.ORCID 0000-0002-9724-4743
Neo Wee ThongDepartment of Diagnostic Imaging, National University Health System, Singapore 119228, Singapore.
Lee Guan HueiDivision of Gastroenterology and Hepatology, National University Health System, Singapore 119228, Singapore.ORCID 0000-0002-8652-6403
Lim Seng GeeDivision of Gastroenterology and Hepatology, National University Health System, Singapore 119228, Singapore.
Low How ChengDivision of Gastroenterology and Hepatology, National University Health System, Singapore 119228, Singapore.
Lee Yin MeiDivision of Gastroenterology and Hepatology, National University Health System, Singapore 119228, Singapore.
Prem ThurairajahDivision of Gastroenterology and Hepatology, National University Health System, Singapore 119228, Singapore.
Lim Jia ChenDivision of Gastroenterology and Hepatology, National University Health System, Singapore 119228, Singapore.
Cheng Han NgDepartment of Medicine, Yong Loo Yin School of Medicine, National University of Singapore, Singapore 119077, Singapore.
Wen Hui LimDepartment of Medicine, Yong Loo Yin School of Medicine, National University of Singapore, Singapore 119077, Singapore.
Darren Jun Hao TanDepartment of Medicine, Yong Loo Yin School of Medicine, National University of Singapore, Singapore 119077, Singapore.
Da Costa MaureenDivision of Hepatobiliary Surgery, National University Health System, Singapore 119228, Singapore.
Kow Wei Chieh AlfredDivision of Hepatobiliary Surgery, National University Health System, Singapore 119228, Singapore.
Iyer Shridar GanpathiDivision of Hepatobiliary Surgery, National University Health System, Singapore 119228, Singapore.
Tan Poh SengDivision of Gastroenterology and Hepatology, National University Health System, Singapore 119228, Singapore.
Dan Yock YoungDivision of Gastroenterology and Hepatology, National University Health System, Singapore 119228, Singapore.
National University Health System · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The guidelines recommend radiofrequency ablation (RFA) for early hepatocellular carcinomas that are less than 3 cm and trans-arterial chemoembolization (TACE) for intermediate-stage tumors. Real-world patient and tumor factors commonly limit strict adherence to the guidelines. We aimed to compare the clinical outcomes for TACE and RFA in early HCC. All consecutive patients from 2010 to 2014 that were treated with locoregional therapy at our institution were enrolled. The decision for TACE or RFA was based on tumor location, stage and technical accessibility for ablation. A subgroup analysis was performed for patients with tumors less than 3 cm. A total of 168 patients underwent TACE while 56 patients underwent RFA. Patients treated with TACE and RFA had 1- and 5-year survival rates of 84.7% and 39.8% versus 91.5% and 51.5%, respectively (

Indexed as

hepatocellular carcinomaradiofrequency ablationtransarterial chemoembolization

Identifiers

PMID36289623
PMCPMC9598932
OpenAlexW4296992767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.